Peroxisome Proliferator-Activated Receptors Protect against Apoptosis via 14-3-3
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Cites background from "Peroxisome Proliferator-Activated R..."
...Yet, while PPARs have been identified as key regulators of inflammatory and immune responses, the role of PPARβ/δ in modulating inflammation during regeneration is poorly characterized....
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...This anti-apoptotic pathway is shared by all PPARs [65]....
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References
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"Peroxisome Proliferator-Activated R..." refers background in this paper
...Mitochondrial membrane potential is maintained, and release of pro-apoptotic cofactors such as cytochrome C and Diablo is blocked when cells are challenged by oxidative stress and cytotoxic insults [58]....
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3,587 citations
"Peroxisome Proliferator-Activated R..." refers background in this paper
...Ligand-activated PPARγ exerts its biological actions by suppressing the expression of proinflammatory genes through NF-κB-dependent transcriptional mechanism [39, 40]....
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2,866 citations
"Peroxisome Proliferator-Activated R..." refers background in this paper
...Ligand-activated PPARγ exerts its biological actions by suppressing the expression of proinflammatory genes through NF-κB-dependent transcriptional mechanism [39, 40]....
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2,731 citations
2,447 citations