Perspective: The physics, diagnostics, and applications of atmospheric pressure low temperature plasma sources used in plasma medicine
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In this article, the authors used low temperature plasma discharges as sources of chemically reactive species that can be transported to interact with biological media, cells, and tissues and induce impactful biological effects.Abstract:
Low temperature plasmas have been used in various plasma processing applications for several decades. But it is only in the last thirty years or so that sources generating such plasmas at atmospheric pressure in reliable and stable ways have become more prevalent. First, in the late 1980s, the dielectric barrier discharge was used to generate relatively large volume diffuse plasmas at atmospheric pressure. Then, in the early 2000s, plasma jets that can launch cold plasma plumes in ambient air were developed. Extensive experimental and modeling work was carried out on both methods and much of the physics governing such sources was elucidated. Starting in the mid-1990s, low temperature plasma discharges have been used as sources of chemically reactive species that can be transported to interact with biological media, cells, and tissues and induce impactful biological effects. However, many of the biochemical pathways whereby plasma affects cells remain not well understood. This situation is changing rather ...read more
Citations
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References
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Applied Plasma Medicine
Gregory Fridman,Gary Friedman,Alexander Gutsol,Anatoly B. Shekhter,Victor N. Vasilets,Alexander Fridman +5 more
TL;DR: Non-equilibrium plasmas will be shown to be non-destructive to tissue, safe, and effective in inactivation of various parasites and foreign organisms.
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The atmospheric-pressure plasma jet: a review and comparison to other plasma sources
TL;DR: In this paper, the physics and chemistry of the plasma jet and other atmospheric pressure sources are reviewed, including transferred arcs, plasma torches, corona discharges, and dielectric barrier discharges.
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The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology
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Low Temperature Plasma-Based Sterilization: Overview and State-of-the-Art
TL;DR: Low temperature, high pressure, non-equilibrium plAsmas are now routinely used in several material processing applications, and in some cases are competing with low pressure plasmas in areas where these have historically been dominant.
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Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms
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