Pharmaceuticals and personal care products in the environment: what are the big questions?
Alistair B.A. Boxall,Murray A. Rudd,Bryan W. Brooks,Daniel J. Caldwell,Kyungho Choi,Silke Hickmann,Elizabeth Innes,Kim Ostapyk,Jane P. Staveley,Tim Verslycke,Gerald T. Ankley,Karen F. Beazley,Scott E. Belanger,Jason P. Berninger,Pedro Carriquiriborde,Anja Coors,Paul C. DeLeo,Scott D. Dyer,Jon F. Ericson,François Gagné,John P. Giesy,Todd Gouin,Lars K Hallstrom,Maja V. Karlsson,D. G. Joakim Larsson,James M. Lazorchak,Frank Mastrocco,Alison McLaughlin,Mark E. McMaster,Roger D. Meyerhoff,Roberta Moore,Joanne L. Parrott,Jason Snape,Richard Murray-Smith,Mark R. Servos,Paul K. Sibley,Juerg Oliver Straub,Nora D. Szabo,Edward Topp,Gerald R. Tetreault,Vance L. Trudeau,Glen Van Der Kraak +41 more
Reads0
Chats0
TLDR
This exercise prioritized the most critical questions regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas.Abstract:
Background: Over the past 10–15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and p...read more
Citations
More filters
Journal ArticleDOI
Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment
Anekwe Jennifer Ebele,Mohamed Abou-Elwafa Abdallah,Mohamed Abou-Elwafa Abdallah,Stuart Harrad +3 more
TL;DR: A review of the current state-of-the-art on PPCPs in the freshwater aquatic environment is presented in this article, where the environmental risk posed by these contaminants is evaluated in light of the persistence, bioaccumulation and toxicity criteria.
Journal ArticleDOI
Occurrences and removal of pharmaceuticals and personal care products (PPCPs) in drinking water and water/sewage treatment plants: A review
TL;DR: The aim of this review is to provide a comprehensive summary of the removal and fate of PPCPs in different treatment facilities as well as the optimum methods for their elimination in STP and WTP systems.
Journal ArticleDOI
Pharmaceuticals in the environment--Global occurrences and perspectives.
Tim aus der Beek,Frank-Andreas Weber,Axel Bergmann,Silke Hickmann,Ina Ebert,Arne Hein,Anette Küster +6 more
TL;DR: It is concluded that pharmaceuticals are a global challenge calling for multistakeholder approaches to prevent, reduce, and manage their entry into and presence in the environment, such as those being discussed under the Strategic Approach to International Chemicals Management, a UN Environment Program.
Journal ArticleDOI
Pharmaceuticals and personal care products in the aquatic environment in China: a review.
TL;DR: The results of SLERA revealed that the hot spots for PPCP pollution were those river waters affected by the megacities with high density of population, such as Beijing, Tianjin, Guangzhou and Shanghai.
Journal ArticleDOI
Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations.
TL;DR: This work shows that a benzodiazepine anxiolytic drug (oxazepam) alters behavior and feeding rate of wild European perch at concentrations encountered in effluent-influenced surface waters, and alters animal behaviors that are known to have ecological and evolutionary consequences.
References
More filters
Journal ArticleDOI
Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.
Dana W. Kolpin,Edward T. Furlong,Michael T. Meyer,E. Michael Thurman,Steven D. Zaugg,Larry B. Barber,Herbert T. Buxton +6 more
TL;DR: The U.S. Geological Survey used five newly developed analytical methods to measure concentrations of 95 organic wastewater contaminants (OWCs) in water samples from a network of 139 streams across 30 states during 1999 and 2000 as mentioned in this paper.
Journal ArticleDOI
Occurrence of antibiotics in the aquatic environment.
TL;DR: From the large number of ground water samples that were taken from agricultural areas in Germany, no contamination by antibiotics was detected except for two sites, which indicates that intake from veterinary applications to the aquatic environment is of minor importance.
Journal ArticleDOI
Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
Gerald T. Ankley,Richard S. Bennett,Russell J. Erickson,Dale J. Hoff,Michael W. Hornung,Rodney D. Johnson,David R. Mount,John W. Nichols,Christine L. Russom,Patricia K. Schmieder,Jose A. Serrrano,Joseph E. Tietge,Daniel L. Villeneuve +12 more
TL;DR: A framework designed for this purpose, the adverse outcome pathway (AOP), is discussed, a conceptual construct that portrays existing knowledge concerning the linkage between a direct molecular initiating event and an adverse outcome at a biological level of organization relevant to risk assessment.
Journal ArticleDOI
Diclofenac residues as the cause of vulture population decline in Pakistan
J. Lindsay Oaks,Martin Gilbert,Munir Z. Virani,Richard T. Watson,Carol U. Meteyer,Bruce A. Rideout,H. L. Shivaprasad,Shakeel Ahmed,Muhammad Jamshed Iqbal Chaudhry,Muhammad Arshad,Shahid Mahmood,Ahmad Ali,Aleem Ahmed Khan +12 more
TL;DR: Results are provided that directly correlate residues of the anti-inflammatory drug diclofenac with renal failure and renal failure in the Oriental white-backed vulture (OWBV) and it is proposed that residues of veterinary diclotenac are responsible for the OWBV decline.
Book
Biomarkers: Biochemical, Physiological, and Histological Markers of Anthropogenic Stress
TL;DR: Research needs metabolic products as biomarkers metabolites of foreign chemicals endogenous metabolites proteins cytochrome P450 metallothioneins stress proteins conjugation enzymes to meet research needs.