Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.
Citations
17 citations
17 citations
Cites methods from "Pharmacotherapy for neuropathic pai..."
...Nonhuman primates (NHP) are phylogenetically closer to humans than rodents and may show drug responses that parallel those of humans....
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...Abbreviations BUN, blood urea nitrogen; CIPN, chemotherapy-induced peripheral neuropathy; NHP, nonhuman primate....
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...The behavioral assay used in the current study is a modification of the NHP tail withdrawal test (Dykstra and Woods 1986)....
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...If such is the case, then preclinical testing of novel treatments for CIPN and elaborating clinical CIPN mechanism will need to incorporate animals such as NHP....
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...The overall differential pharmacology between NHP and rodents suggests species-specific mechanisms of oxaliplatin-induced neuropathy....
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17 citations
17 citations
17 citations
Cites background or methods from "Pharmacotherapy for neuropathic pai..."
...treatment of CPSP usually involves neuropathic analgesics and sometimes neuromodulation, but remains challenging as satisfactory pain relief is achieved only in a minority of patients.(22,24) Animal models are experimental preparations developed in...
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...CPSP, the clinical efficacy of analgesics in CPSP is generally low.(24) With pregabalin for instance, the number needed to treat for a 50% pain reduction in CPSP was 27....
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...With pregabalin for instance, the number needed to treat for a 50% pain reduction in CPSP was 27.(24,42)...
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References
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