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Journal ArticleDOI

Phd by thesis

01 Apr 1988-Nature (Nature Publishing Group)-Vol. 332, Iss: 6166, pp 676-676
TL;DR: In this paper, a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) is presented.
Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

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TL;DR: The theory of Thom spectra and the associated obstruction theory for orientations was reviewed and extended in this paper, and two approaches to the theory were developed and compared to one another and to the classical theory, in order to characterize the Thom spectrum functor from the perspective of Morita theory.
Abstract: We review and extend the theory of Thom spectra and the associated obstruction theory for orientations. We recall (from May, Quinn, and Ray) that a commutative ring spectrum A has a spectrum of units gl(A). To a map of spectra f: b -> bgl(A), we associate a commutative A-algebra Thom spectrum Mf, which admits a commutative A-algebra map to R if and only if b -> bgl(A) -> bgl(R) is null. If A is an associative ring spectrum, then to a map of spaces f: B -> BGL(A) we associate an A-module Thom spectrum Mf, which admits an R-orientation if and only if B -> BGL(A) -> BGL(R) is null. We also note that BGL(A) classifies the twists of A-theory. We develop and compare two approaches to the theory of Thom spectra. The first involves a rigidified model of A-infinity and E-infinity spaces. Our second approach is via infinity categories. In order to compare these approaches to one another and to the classical theory, we characterize the Thom spectrum functor from the perspective of Morita theory.

70 citations


Cites background from "Phd by thesis"

  • ...Rekha Santhanam [San08] has shown that the work of May and Thomason [MT78] can be used to prove that the category of C-spaces is Quillen equivalent to the category of Γ-spaces....

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Journal ArticleDOI
TL;DR: This paper will give an overview of quantum computation from the point of view of a complexity theorist and see that one can think of BQP as yet another complexity class and study its power without focusing on the physical aspects behind it.

70 citations


Cites background from "Phd by thesis"

  • ...Li [Li93] and Fenner, Fortnow, Kurtz and Li [FFKL93] defined and studied the class AWPP (stands for Almost-Wide Probabilistic Polynomial-time) extensively....

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Journal ArticleDOI
TL;DR: In this article, the hydrogen and deuterium atom addition reactions of CO to form HCO and DCO are addressed by Harmonic Quantum Transition State Theory calculations, where it is found that quantum tunneling leads to substantial rates of reaction.

69 citations


Cites background or methods or result from "Phd by thesis"

  • ...Then the calculation of the action becomes [21,22,31]...

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  • ...Thermal rate constants have been calculated using Harmonic Quantum Transition State Theory (HQTST) [21,22], which is a recent implementation of instanton theory [23–33]....

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  • ...HQTST was found to give rate constants in excellent agreement with exact quantum dynamics for model 2D systems down into the ‘deep tunneling’ regime at low temperatures [21]....

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  • ...Qr is the reactant partition function, Ds = s/P = h/kBT is the imaginary time step, kj are the normal mode frequencies of the instanton chain, and S0 is the action of the ‘zero mode’, which arises due to permutation of the images in the chain [21,22]....

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Journal ArticleDOI
19 Jun 2018-Placenta
TL;DR: Senescence markers increase in normal placentas with gestational age, and are exaggerated in post-mature and pathological cases, and the consequent pro-inflammatory senescence-associated secretory phenotype may contribute to the pathophysiology of pre-eclampsia.

69 citations


Cites methods from "Phd by thesis"

  • ...Paraffin and EM blocks of term healthy placentas (N=5) and postmature placentas (delivered 7–20 d after due date, N= 6) were from an archival collection from the University of Manchester [30]....

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  • ...Tissue collection – post-mature placentas and their term controls Paraffin and EM blocks of term healthy placentas (N=5) and postmature placentas (delivered 7–20 d after due date, N= 6) were from an archival collection from the University of Manchester [30]....

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  • ...Given the rise in p21 with gestational age, we quantified the number of p21-positive syncytiotrophoblast nuclei in an archival collection of post-mature placentas delivered 7–20 days following the due date [30], and observed a significant increase compared to term controls (5....

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  • ...Contents lists available at ScienceDirect Placenta journal homepage: www.elsevier.com/locate/placenta Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas Tereza Cindrova-Daviesa,∗, Norah M.E. Fogartya,b, Carolyn J.P. Jonesc, John Kingdomd, Graham J. Burtona a Centre for Trophoblast Research, University of Cambridge, UK b Francis Crick Institute, London, UK cMaternal and Fetal Health Research Centre Division of Developmental Biology & Medicine School of Medical Sciences Faculty of Biology, Medicine and Health University of Manchester, Manchester Academic Health Science Centre, St Mary's Hospital Oxford Road Manchester M13 9 WL, UK dMount Sinai Hospital, University of Toronto, Canada A R T I C L E I N F O...

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Journal ArticleDOI
TL;DR: In this article, a fundamental kinetic model for the hydrogenation of toluene over platinum has been constructed, based on detailed first-principles density functional theory calculations for the benzene over Pt(111), enabling easy interpretation and evaluation of the parameters appearing in the rate equation.

69 citations


Cites background or methods from "Phd by thesis"

  • ...The calculated adsorption enthalpy of cy hexane is−27 kJ/mol [1,20]....

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  • ...Previously, we carried out an extensive set of ab initio culations to obtain a detailed understanding of the mecha of benzene hydrogenation to cyclohexane [1,17,20,21] ....

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  • ...The adsorption and dehydrogenation of cyclic C 6 molecules on transition metals has also received considerable atte from both the surface science and theoretical communi From these studies, a fairly consistent picture has emerged ious investigators have combined data from spectroscopic surface science studies with results from density functional ory (DFT) to gain a clear understanding of the adsorption benzene on Pt(111), Pd(111), Rh(111), and Ni(111) [ 7,18]and of the adsorption of cyclohexadiene [19] and cyclohexene[20] on Pt(111)....

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References
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Journal ArticleDOI
TL;DR: A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+ using an 8-coordinate tetracarboxylate chelating site with stilbene chromophores that offer up to 30-fold brighter fluorescence.

21,582 citations


"Phd by thesis" refers background in this paper

  • ...members of this group were produced by Tsien and colleagues [1, 10, 11]....

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  • ...The introduction of Ca 2+ -sensitive fluorescent dyes more than twenty years ago and their permanent improvement [10] enabled investigators to gain unprecedented insights into the mechanisms of cellular signalling....

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ReportDOI
01 Nov 1990
TL;DR: This report will establish methods for performing a domain analysis and describe the products of the domain analysis process to illustrate the application of domain analysis to a representative class of software systems.
Abstract: : Successful Software reuse requires the systematic discovery and exploitation of commonality across related software systems. By examining related software systems and the underlying theory of the class of systems they represent, domain analysis can provide a generic description of the requirements of that class of systems and a set of approaches for their implementation. This report will establish methods for performing a domain analysis and describe the products of the domain analysis process. To illustrate the application of domain analysis to a representative class of software systems, this report will provide a domain analysis of window management system software.

4,420 citations

Journal ArticleDOI
TL;DR: The straw person model (SPM) as mentioned in this paper has been proposed to explain the orientation effects of active galactic nuclei (AGN) and quasars in the line of sight (LOS) images.
Abstract: Because the critical central regions of Active Galactic Nuclei (AGN) and quasars are strongly nonspherical but spatially unresolved, orientation effects have been the source of much confusion. In fact, it now appears that much of the variety in AGN types is just the result of varying orientation relative to the line of sight. We can define an extreme hypothesis,, the straw person model (SPM), in which there are two basic types of AGN: the radio quiets and the radio louds. For each type there is a range in intrinsic luminosity, and the luminosity controls some properties such as the Fanaroff and Riley classes. However, at a given intrinsic luminosity, all other properties such as spectroscopic classification and VLBI component speeds are ascribed to orientation. This model is only a caricature of the unification idea, and is already ruled out on many grounds, but it will be useful for organizing the discussion. I’ll describe what I consider to be convincing evidence that orientation effects are important and widespread. The true situation may be in some sense half way between the SPM and the hypothesis that orientation doesn’t affect classification at aIl. To us optimists, the orienration cup is half full rather than half empty. Although it is too soon to say for sure, the hypothesis that most objects’ classifications would be different if seen from other directions is a tenable one today.

4,005 citations

Journal ArticleDOI
TL;DR: This Review assembles the current knowledge on the isolation of microfibrillated cellulose from wood and its application in nanocomposites; the preparation of nanocrystalline cellulose and its use as a reinforcing agent; and the biofabrication of bacterial nanocellulose, as well as its evaluation as a biomaterial for medical implants.
Abstract: Cellulose fibrils with widths in the nanometer range are nature-based materials with unique and potentially useful features. Most importantly, these novel nanocelluloses open up the strongly expanding fields of sustainable materials and nanocomposites, as well as medical and life-science devices, to the natural polymer cellulose. The nanodimensions of the structural elements result in a high surface area and hence the powerful interaction of these celluloses with surrounding species, such as water, organic and polymeric compounds, nanoparticles, and living cells. This Review assembles the current knowledge on the isolation of microfibrillated cellulose from wood and its application in nanocomposites; the preparation of nanocrystalline cellulose and its use as a reinforcing agent; and the biofabrication of bacterial nanocellulose, as well as its evaluation as a biomaterial for medical implants.

3,452 citations

Journal ArticleDOI
TL;DR: The solid electrolyte interphase (SEI) is a protecting layer formed on the negative electrode of Li-ion batteries as a result of electrolyte decomposition, mainly during the first cycle as discussed by the authors.

2,386 citations