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Journal ArticleDOI

Phd by thesis

01 Apr 1988-Nature (Nature Publishing Group)-Vol. 332, Iss: 6166, pp 676-676
TL;DR: In this paper, a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) is presented.
Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

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Citations
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Journal ArticleDOI
TL;DR: In this article, an update of the Standard Model fit to electroweak precision data is presented, which includes new experimental results on the top-quark mass, W mass and width, and the Higgs-boson mass bounds from LEP, Tevatron and the LHC.
Abstract: We present an update of the Standard Model fit to electroweak precision data. We include newest experimental results on the top-quark mass, the W mass and width, and the Higgs-boson mass bounds from LEP, Tevatron and the LHC. We also include a new determination of the electromagnetic coupling strength at the Z pole. We find for the Higgs-boson mass $91^{+30}_{-23}~\mbox{GeV}$ and $120^{+12}_{-5}~\mbox{GeV}$ when not including and including the direct Higgs searches, respectively. From the latter fit we indirectly determine the W mass to be $(80.360^{+0.014}_{-0.013})~\mbox{GeV}$ . We exploit the data to determine experimental constraints on the oblique vacuum polarisation parameters, and confront these with predictions from the Standard Model (SM) and selected SM extensions. By fitting the oblique parameters to the electroweak data we derive allowed regions in the BSM parameter spaces. We revisit and consistently update these constraints for a fourth fermion generation, two Higgs doublet, inert Higgs and littlest Higgs models, models with large, universal or warped extra dimensions and technicolour. In most of the models studied a heavy Higgs boson can be made compatible with the electroweak precision data.

257 citations


Cites methods from "Phd by thesis"

  • ...Small additional correction factors, determined from a comparison with the Fortran ZFITTER package [22, 26], are used to accommodate heavy Higgs masses [34]....

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Journal ArticleDOI
TL;DR: In this paper, the results for the ΛN and ΣN interactions obtained at next-to-leading order in chiral effective field theory are reported, at the order considered there are contributions from one-and two-pseudoscalar-meson exchange diagrams and from four-baryon contact terms without and with two derivatives.

257 citations


Cites background from "Phd by thesis"

  • ...Information onΛp scattering, specifically on the scattering lengths, might emerge from ongoing studies of the final-state interac tion in production reactions likepp → KΛp [4] and γd→ KΛn [5]....

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Proceedings ArticleDOI
01 Feb 1992
TL;DR: This paper connects and explains the geometry of interaction and Lamping's graphs, which offer a new understanding of computation, as well as ideas for efficient and correct implementations.
Abstract: Lamping discovered an optimal graph-reduction implementation of the l-calculus. Simultaneously, Girard invented the geometry of interaction, a mathematical foundation for operational semantics. In this paper, we connect and explain the geometry of interaction and Lamping's graphs. The geometry of interaction provides a suitable semantic basis for explaining and improving Lamping's system. On the other hand, graphs similar to Lamping's provide a concrete representation of the geometry of interaction. Together, they offer a new understanding of computation, as well as ideas for efficient and correct implementations.

257 citations

Journal ArticleDOI
01 Mar 2017
TL;DR: The metal-site validation tool CheckMyMetal is described, with examples to follow.
Abstract: Metals are essential in many biological processes, and metal ions are modeled in roughly 40% of the macromolecular structures in the Protein Data Bank (PDB). However, a significant fraction of these structures contain poorly modeled metal-binding sites. CheckMyMetal (CMM) is an easy-to-use metal-binding site validation server for macromolecules that is freely available at http://csgid.org/csgid/metal_sites. The CMM server can detect incorrect metal assignments as well as geometrical and other irregularities in the metal-binding sites. Guidelines for metal-site modeling and validation in macromolecules are illustrated by several practical examples grouped by the type of metal. These examples show CMM users (and crystallographers in general) problems they may encounter during the modeling of a specific metal ion.

255 citations


Cites background from "Phd by thesis"

  • ...Consequently, it would be imprecise to define a single typical distance for a given iron–ligand coordination bond, especially in the case of iron–nitrogen interactions (Pidcock, 1995; Zheng et al., 2017)....

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Journal ArticleDOI
TL;DR: It is shown that fluorescence excitation is in all cases limited by photolysis from higher-excited electronic states, and comparison with experimental data and an exact theoretical model show that only minor deviations between the different theoretical approaches can be observed for high-pulsed excitation irradiances.
Abstract: Under high-excitation irradiance conditions in one- and two-photon induced fluorescence microscopy, the photostability of fluorescent dyes is of crucial importance for the detection sensitivity of single molecules and for the contrast in fluorescence imaging. Herein, we report on the dependence of photobleaching on the excitation conditions, using the dye Rhodamine 6G as a typical example. The different excitation modes investigated include 1) one-photon excitation into the first-excited singlet state in the range of 500 to 528 nm by continuous wave and picosecond-pulsed lasers and 2) two- and one-photon excitation to higher-excited singlet states at 800 and 350 nm, respectively, by femtosecond pulses. Experimental strategies are presented, which allow resolving the photophysics. From single-molecule trajectories and fluorescence correlation spectroscopy, as well as with a simple theoretical model based on steady-state solutions of molecular rate equation analysis, we determined the underlying photobleaching mechanisms and quantified the photokinetic parameters describing the dependence of the fluorescence signal on the excitation irradiance. The comparison with experimental data and an exact theoretical model show that only minor deviations between the different theoretical approaches can be observed for high-pulsed excitation irradiances. It is shown that fluorescence excitation is in all cases limited by photolysis from higher-excited electronic states. In contrast to picosecond-pulsed excitation, this is extremely severe for both one- and two-photon excitation with femtosecond pulses. Furthermore, the photostability of the higher-excited electronic states is strongly influenced by environmental conditions, such as polarity and temperature.

255 citations


Cites background from "Phd by thesis"

  • ...[43, 50] In the case of two-photon excitation, it has a value of Iav = I0/2 .([82])...

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References
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Journal ArticleDOI
TL;DR: A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+ using an 8-coordinate tetracarboxylate chelating site with stilbene chromophores that offer up to 30-fold brighter fluorescence.

21,582 citations


"Phd by thesis" refers background in this paper

  • ...members of this group were produced by Tsien and colleagues [1, 10, 11]....

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  • ...The introduction of Ca 2+ -sensitive fluorescent dyes more than twenty years ago and their permanent improvement [10] enabled investigators to gain unprecedented insights into the mechanisms of cellular signalling....

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ReportDOI
01 Nov 1990
TL;DR: This report will establish methods for performing a domain analysis and describe the products of the domain analysis process to illustrate the application of domain analysis to a representative class of software systems.
Abstract: : Successful Software reuse requires the systematic discovery and exploitation of commonality across related software systems. By examining related software systems and the underlying theory of the class of systems they represent, domain analysis can provide a generic description of the requirements of that class of systems and a set of approaches for their implementation. This report will establish methods for performing a domain analysis and describe the products of the domain analysis process. To illustrate the application of domain analysis to a representative class of software systems, this report will provide a domain analysis of window management system software.

4,420 citations

Journal ArticleDOI
TL;DR: The straw person model (SPM) as mentioned in this paper has been proposed to explain the orientation effects of active galactic nuclei (AGN) and quasars in the line of sight (LOS) images.
Abstract: Because the critical central regions of Active Galactic Nuclei (AGN) and quasars are strongly nonspherical but spatially unresolved, orientation effects have been the source of much confusion. In fact, it now appears that much of the variety in AGN types is just the result of varying orientation relative to the line of sight. We can define an extreme hypothesis,, the straw person model (SPM), in which there are two basic types of AGN: the radio quiets and the radio louds. For each type there is a range in intrinsic luminosity, and the luminosity controls some properties such as the Fanaroff and Riley classes. However, at a given intrinsic luminosity, all other properties such as spectroscopic classification and VLBI component speeds are ascribed to orientation. This model is only a caricature of the unification idea, and is already ruled out on many grounds, but it will be useful for organizing the discussion. I’ll describe what I consider to be convincing evidence that orientation effects are important and widespread. The true situation may be in some sense half way between the SPM and the hypothesis that orientation doesn’t affect classification at aIl. To us optimists, the orienration cup is half full rather than half empty. Although it is too soon to say for sure, the hypothesis that most objects’ classifications would be different if seen from other directions is a tenable one today.

4,005 citations

Journal ArticleDOI
TL;DR: This Review assembles the current knowledge on the isolation of microfibrillated cellulose from wood and its application in nanocomposites; the preparation of nanocrystalline cellulose and its use as a reinforcing agent; and the biofabrication of bacterial nanocellulose, as well as its evaluation as a biomaterial for medical implants.
Abstract: Cellulose fibrils with widths in the nanometer range are nature-based materials with unique and potentially useful features. Most importantly, these novel nanocelluloses open up the strongly expanding fields of sustainable materials and nanocomposites, as well as medical and life-science devices, to the natural polymer cellulose. The nanodimensions of the structural elements result in a high surface area and hence the powerful interaction of these celluloses with surrounding species, such as water, organic and polymeric compounds, nanoparticles, and living cells. This Review assembles the current knowledge on the isolation of microfibrillated cellulose from wood and its application in nanocomposites; the preparation of nanocrystalline cellulose and its use as a reinforcing agent; and the biofabrication of bacterial nanocellulose, as well as its evaluation as a biomaterial for medical implants.

3,452 citations

Journal ArticleDOI
TL;DR: The solid electrolyte interphase (SEI) is a protecting layer formed on the negative electrode of Li-ion batteries as a result of electrolyte decomposition, mainly during the first cycle as discussed by the authors.

2,386 citations