Phytochelatins and their roles in heavy metal detoxification
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...From a variety of experimental approaches the involvement of PCs in the detoxification of Cd and As (Cobbett, 2000,; Schmöger et al., 2000) appears definite as they could also be linked to the differential heritable tolerance to Cd in Arabidopsis thaliana (Howden et al., 1995) and As in Holcus…...
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...From a variety of experimental approaches the involvement of PCs in the detoxification of Cd and As ( Cobbett, 2000, ; Schmo ¨ger et al., 2000) appears definite as they could also be linked to the differential heritable tolerance to Cd in Arabidopsis thaliana (Howden et al., 1995) and As in Holcus lanatus (Hartley-Whitaker et al., 2001)....
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1,096 citations
Cites background from "Phytochelatins and their roles in h..."
...Induced Phytoextraction or Chelate assisted Phytoextraction Within the plant cell heavy metal may trigger the production of oligopeptide ligands known as phytochelatins (PCs) and metallothioneins (MTs) [67]....
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References
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"Phytochelatins and their roles in h..." refers background in this paper
...There is also circumstantial evidence supporting post-transcriptional regulation of GCS expression in addition to the well-recognized regulation of GCS activity through GSH feedback inhibition (May et al., 1998; Noctor and Foyer, 1998)....
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2,189 citations
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"Phytochelatins and their roles in h..." refers background in this paper
...In addition, a number of structural variants, for example, (g-Glu-Cys)n-bAla, (g-Glu-Cys)n-Ser, and (g-Glu-Cys)n-Glu, have been identified in some plant species (Rauser, 1995, 1999; Zenk, 1996)....
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...Numerous physiological, biochemical, and genetic studies have confirmed that GSH (or, in some cases, related compounds) is the substrate for PC biosynthesis (Rauser, 1995, 1999; Zenk, 1996)....
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...Other more recent reviews are by Zenk (1996) and Rauser (1999)....
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...These observations have been interpreted to indicate a role for PCs in the homeostasis of essential metal ion metabolism (Rauser, 1995, 1999; Zenk, 1996)....
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...In addition, roles for PCs in Fe or sulfur metabolism have also been proposed (Zenk, 1996; Sanita di Toppi and Gabbrielli, 1999)....
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892 citations
"Phytochelatins and their roles in h..." refers background in this paper
...Grill et al. (1989) first identified an enzyme activity from cultured cells of Silene cucubalis that synthesized PCs from GSH by transferring a g-Glu-Cys moiety from a donor to an acceptor molecule....
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...It has been detected in S. cucubalis cells grown in culture medium (Grill et al., 1989), and in tomato (Chen et al., 1997) and Arabidopsis (Howden et al., 1995) plants grown in soil or agar medium, in the presence of only trace levels of essential heavy metals....
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