Placental trophoblast cell differentiation: Physiological regulation and pathological relevance to preeclampsia
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Cites background from "Placental trophoblast cell differen..."
...Moreover, miRNA expression in the placenta is regulated by environment factors [22], signaling pathways [59], and epigenetic modification [60]....
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212 citations
Cites methods from "Placental trophoblast cell differen..."
...Our analysis supported a bifurcating model with VCTB differentiating bidirectionally into SCTB and EVTB (64)....
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211 citations
References
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"Placental trophoblast cell differen..." refers background in this paper
...First, the individual miRNA gene is transcribed into a primary transcript (pri-miRNA) by RNA polymerase II (Bartel, 2004; Cai et al., 2004)....
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"Placental trophoblast cell differen..." refers background in this paper
...Since the establishment of human embryonic stem cells (ESCs) a decade ago (Thomson et al., 1998), evidence has increased that human ESCs are useful models with which to examine the emergence and differentiation of trophoblasts....
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...Thomson et al. first reported the spontaneous differentiation of human and nonhuman primate ESCs to the trophoblast lineage (Thomson et al., 1998, 1995, 1996)....
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