Plasma cell granuloma of the stomach. A report of a case and review of the literature
TL;DR: It is considered that plasma cell granuloma may well be classified into one of the sub‐types of the postinflammatory pseudotumor in a 33‐year‐old man surgically treated as an advanced carcinoma of the cardia.
Abstract: A case of plasma cell granuloma of the stomach in a 33-year-old man, surgically treated as an advanced carcinoma of the cardia, is reported. Histologically, the lesion is of nonneoplastic nature and appears to be inflammatory in origin with unknown etiologic causes. The histologic and pathogenetic differences of this particular lesion from plasmacytoma are especially emphasized. It is considered that plasma cell granuloma may well be classified into one of the sub-types of the postinflammatory pseudotumor. The patient has been followed, and no clinical evidence of recurrent disorder for 2 years postoperatively has been observed.
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TL;DR: Clinicopathologic findings in 32 cases of inflammatory pseudotumor of the lung are described, and most or all cases are believed to originate as organizing pneumonia.
321 citations
TL;DR: In conclusion, inflammatory myofibroblastic tumors of the gastrointestinal tract are extremely rare and differ clinically, histologically, and immunohistochemically from inflammatory fibroid polyps.
143 citations
TL;DR: One child, with the tumor arising from the urinary bladder, was originally diagnosed as having a malignant sarcoma and underwent pelvic exenteration and chemotherapy for this subsequently-proven benign lesion, which pointed out the importance of pathologic differentiation of these lesions from malignancy with early appropriate surgery.
134 citations
TL;DR: A case of plasma cell granuloma (inflammatory pseudotumor) arising in the meninges of cervical spinal cord of a 37‐year‐old Japanese man is presented, the first case, to the authors' knowledge, of this type “tumor” in the spinal cord meninges.
Abstract: A case of plasma cell granuloma (inflammatory pseudotumor) arising in the meninges of cervical spinal cord of a 37-year-old Japanese man is presented. The diagnosis was made by analogy with the similar lesions known in the lung. Its histology was characterized by infiltration of three kinds of cells; histiocytes with slight epithelioid appearance, plasma cells with numerous Russell bodies, and lymphocytes. Electron microscopy of the formalin-fixed tissue was useful for the identification of these cells, particularly of histiocytes. Although extrapulmonary plasma cell granulomas have been reported, this is the first case, to our knowledge, of this type "tumor" in the spinal cord meninges. Differential diagnoses have been briefly discussed.
117 citations
TL;DR: It is suggested that prior reports of meningiomas with conspicuous plasma cell‐lymphocytic components may in reality be plasma cell granulomas and could be differentiated by electron microscopy.
Abstract: The first case of an intracranial plasma cell granuloma is presented. An associated polyclonal gammopathy was another remarkable feature. Routine and special stains of histologic sections as well as electron microscopy characterized such lesions. Immunofluorescent studies revealed a heterogeneous population of plasma cells. When the granuloma was removed, the polyclonal gammopathy resolved, and neither have recurred with eight months of follow-up. It is suggested that prior reports of meningiomas with conspicuous plasma cell-lymphocytic components may in reality be plasma cell granulomas and could be differentiated by electron microscopy.
111 citations
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TL;DR: The most important anatomic criteria which should arouse suspicion of postinflammatory “tumors” are: generous numbers of inflammatory cells within the mass, maturity of the fibroblastic components, lack of mitotic activity, and remanants of pre-existing parenchyma throughout the mass in the form of elastic fibers.
Abstract: SUMMARY 1. Four postinflammatory “tumors” of the lung are described and compared with three similar ones from the literature. 2. Clinically, the lesions are characterized by a history of infection of the upper or lower respiratory tract and roentgenograms suggestive of tuberculomas or well-circumscribed neoplasms. 3. Morphologically, they closely simulate true tumors, such as xanthoma, xanthofibroma, neurofibroma, fibroma, vascular tumor, or plasma cell tumor. 4. The most important anatomic criteria which should arouse suspicion of postinflammatory “tumors” are: generous numbers of inflammatory cells within the mass, maturity of the fibroblastic components, lack of mitotic activity, and remanants of pre-existing parenchyma throughout the mass in the form of elastic fibers.
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