Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma
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"Plasma miRNAs as early biomarkers f..." refers background in this paper
...MicroRNAs (miRNAs) are a family of endogenous RNAs that play important roles in regulating gene expression by degrading target mRNAs or blocking their translation.(3) A number of studies have reported that the altered expression of circulating miRNAs is associated with many diseases, including HCC....
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"Plasma miRNAs as early biomarkers f..." refers background in this paper
...Binding to argonaute proteins stabilizes circulating miRNAs in the plasma/serum; thus, they are potentially stable noninvasive biomarkers.(7,8) However, tissue specificity and early activation are important properties of specific biomarkers for the early detection of cancer....
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"Plasma miRNAs as early biomarkers f..." refers background in this paper
...Considering the high expression of c-myc in HCC, the miR-17-92 cluster together with c-myc overexpression may play a role in cancer development.(21,22) Four miRNAs (miR-19a-3p, miR19b-3p, miR-20a-3p and miR-92a-3p) from this cluster were Figure 2....
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