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Polystyrene microplastics induced male reproductive toxicity in mice

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TLDR
It is demonstrated that PS-MPs induced male reproductive dysfunctions in mice, which provided new insights into the toxicity of MPs in mammals.
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This article is published in Journal of Hazardous Materials.The article was published on 2021-01-05. It has received 211 citations till now. The article focuses on the topics: Reproductive toxicity & Seminiferous tubule.

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Microplastics are everywhere — but are they harmful?

XiaoZhi Lim
- 04 May 2021 - 
TL;DR: In this paper, the tiny plastic specks that are in marine animals and in us are studied. But the authors are concerned about the impact of these specks on the environment.
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Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

TL;DR: In this article, the effects of polystyrene MPs (PS MPs) on the ovary and its mechanism in rats remained unclear. But, exposure to microplastics had adverse effects on ovarian and could be a potential risk factor for female infertility, which provided new insights into the toxicity of MPs on female reproduction.
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Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells.

TL;DR: In this article, the authors observed accumulation of polystyrene NPs (PS NPs) in mice spleen, lung, kidney, small intestine, large intestine, testis, and brain after oral exposure to PS NPs for 28 days, and NPs were identified to induce cell apoptosis, inflammation, and structure disorder in these tissues.
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Enhanced reproductive toxicities induced by phthalates contaminated microplastics in male mice (Mus musculus).

TL;DR: Compared with virgin MPs and PAEs alone, PAE-contaminated MPs induced enhanced reproductive toxicities manifested by greater alterations in sperm physiology and spermatogenesis, which provide valuable insights into the mechanism of combined toxicity of MPs and other pollutants.
Journal ArticleDOI

Polystyrene microplastics induced female reproductive toxicity in mice

TL;DR: In this article , the reproductive toxicity of polystyrene MPs (PS-MPs) in female mice was evaluated after continued exposure for 35 days, and the results showed that PS-MP exposure induced the inflammation of ovaries and reduced the quality of oocytes in mice, which provided a basis for studying the reproductive toxic mechanism of PSMPs in female mammals.
References
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Journal ArticleDOI

Plastic waste inputs from land into the ocean

TL;DR: This work combines available data on solid waste with a model that uses population density and economic status to estimate the amount of land-based plastic waste entering the ocean, which is estimated to be 275 million metric tons.
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Lost at sea: where is all the plastic?

TL;DR: It is shown that microscopic plastic fragments and fibers are also widespread in the marine environment and may persist for centuries.
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Accumulation and fragmentation of plastic debris in global environments.

TL;DR: Global plastics production and the accumulation of plastic waste are documented, showing that trends in mega- and macro-plastic accumulation rates are no longer uniformly increasing and that the average size of plastic particles in the environment seems to be decreasing.
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Microplastics as contaminants in the marine environment: a review.

TL;DR: Ingestion of microplastics has been demonstrated in a range of marine organisms, a process which may facilitate the transfer of chemical additives or hydrophobic waterborne pollutants to biota.
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