Post-infection depressive, anxiety and post-traumatic stress symptoms: A prospective cohort study in patients with mild COVID-19.
Flavia Ismael,Joao C. S. Bizario,Tatiane Battagin,Beatriz Zaramella,Fabio E. Leal,Julio Torales,Antonio Ventriglio,Megan E. Marziali,Silvia S. Martins,João Mauricio Castaldelli-Maia +9 more
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TLDR
In this article, the authors investigated the association between the number of COVID-19 symptoms at intake and depressive, anxiety and post-traumatic symptoms approximately two months later, adjusting for previous mental health status, time between baseline and outcome, and other confounders.Abstract:
Background It remains unclear whether COVID-19 is associated with psychiatric symptoms during or after the acute illness phase. Being affected by the disease exposes the individual to an uncertain prognosis and a state of quarantine. These factors can predispose individuals to the development of mental symptoms during or after the acute phase of the disease. There is a need for prospective studies assessing psychiatric symptoms in COVID-19 patients in the post-infection period. Methods In this prospective cohort study, nasopharyngeal swabs for COVID-19 tests were collected at patients' homes under the supervision of trained healthcare personnel. Patients who tested positive for COVID-19 and were classified as mild cases (N = 895) at treatment intake were further assessed for the presence of psychiatric symptoms (on average, 56.6 days after the intake). We investigated the association between the number of COVID-19 symptoms at intake and depressive, anxiety and post-traumatic symptoms approximately two months later, adjusting for previous mental health status, time between baseline and outcome, and other confounders. Multivariate logistic regression and generalized linear models were employed for categorical and continuous outcomes, respectively. Results A clinically significant level of depressive, anxiety and post-traumatic stress symptoms were reported by 26.2% (N = 235), 22.4% (N = 201), and 17.3% (N = 155) of the sample. Reporting an increased number of COVID-related symptoms was associated with the presence of clinically significant levels of depressive (aOR = 1.059;95%CI = 1.002–1.119), anxiety (aOR = 1.072;95%CI = 1.012–1.134), and post-traumatic stress (aOR = 1.092;95%CI = 1.024–1.166) symptoms. Sensitivity analyses supported findings for both continuous and categorical measures. Conclusion Exposure to an increased number of COVID-19 symptoms may be associated with depressive, anxiety and post-traumatic symptoms after the acute phase of the disease. These patients should be monitored for the development of psychiatric symptoms after COVID-19 treatment discharge. Early interventions, such as brief interventions of psychoeducation on coping strategies, could benefit these individuals.read more
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Psychological distress and health-related quality of life in patients after hospitalization during the COVID-19 pandemic: A single-center, observational study.
Johan H Vlake,Sanne Wesselius,Michel E van Genderen,Jasper van Bommel,Bianca Boxma-de Klerk,Evert-Jan Wils +5 more
TL;DR: The impact of hospitalization during the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic on psychological well-being and health-related quality of life is expected to be higher due to the exceptional circumstances within and outside the hospital during the pandemic surge as mentioned in this paper.
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The next pandemic: impact of COVID-19 in mental healthcare assistance in a nationwide epidemiological study.
Felipe Ornell,Wyllians Vendramini Borelli,Daniela Benzano,Jaqueline Bohrer Schuch,Helena Ferreira Moura,Helena Ferreira Moura,Anne Orgler Sordi,Felix Kessler,Juliana Nichterwitz Scherer,Lisia von Diemen +9 more
TL;DR: In this article, an ecological time-series study was performed, analyzing mental health appointments before and during the COVID-19 pandemic (from 2016 and 2020) from the Brazilian governmental database.
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Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil.
Geraldo F. Busatto,Adriana Ladeira de Araújo,Alberto José da Silva Duarte,Anna S. Levin,Bruno Fukelmann Guedes,Esper G. Kallas,Fábio de Rezende Pinna,Heraldo Possolo de Souza,Kátia Regina da Silva,Marcio Valente Yamada Sawamura,Marilia Seelaender,Marta Imamura,Michelle Louvaes Garcia,Orestes Vicente Forlenza,Ricardo Nitrini,Rodolfo Furlan Damiano,Vanderson Rocha,Linamara Rizzo Batisttella,Carlos Roberto Ribeiro de Carvalho +18 more
TL;DR: In this article, a prospective observational study of surviving individuals (above 18 years of age) from a cohort of over 3000 subjects with laboratory-confirmed COVID-19 who were treated as inpatients at the largest academic health centre in Sao Paulo, Brazil (Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo).
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Relationship between the severity of persistent symptoms, physical fitness, and cardiopulmonary function in post-COVID-19 condition. A population-based analysis
Amaya Jimeno-Almazán,Alejandro Martínez-Cava,Ángel Buendía-Romero,Francisco Franco-López,José Antonio Sánchez-Agar,Bernardino J. Sánchez-Alcaraz,James J. Tufano,Jesús G. Pallarés,Javier Courel-Ibáñez +8 more
TL;DR: In this article , the authors determined the relationship between physical fitness, cardiopulmonary function and patient-reported severity of symptoms in people with post-COVID-19 condition.
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Post-acute sequelae of SARS-CoV-2 infection: relationship of central nervous system manifestations with physical disability and systemic inflammation
TL;DR: In this paper , the authors investigated associations of latent variable severity with objective indices of persistent physical disability, pulmonary and kidney dysfunction, and C-reactive protein and D-dimer blood levels, measured at the same follow-up assessment.
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