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Journal ArticleDOI

Postmortem toxicology of drugs of abuse

Olaf H. Drummer
- 10 Jun 2004 - 
- Vol. 142, Iss: 2, pp 101-113
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TLDR
Toxicological issues associated with the more common drugs of abuse such as the amphetamines, cannabinoids, cocaine, opioids and the benzodiazepines are reviewed.
About
This article is published in Forensic Science International.The article was published on 2004-06-10. It has received 249 citations till now. The article focuses on the topics: Heroin.

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Citations
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Journal ArticleDOI

Validation of new methods.

TL;DR: Important considerations in analytical method validation will be discussed and may be used as guidance by scientists wishing to develop and validate analytical methods.
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Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals

TL;DR: A solid phase extraction method has been developed and applied in conjunction with a previously reported liquid chromatography tandem mass spectrometry procedure for the determination of illicit drugs and abused pharmaceuticals in treated wastewater and surface water samples at the ng L(-1) level.
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Collection of biological samples in forensic toxicology.

TL;DR: An overview is given on sampling procedures for routinely collected specimens as well as on alternative specimens that may provide additional information on the route and timing of exposure to a specific xenobiotic.
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Alcohol, psychoactive drugs and fatal road traffic accidents in Norway: A case–control study

TL;DR: For most substances, higher ORs were found when studying drivers involved in single vehicle accidents than for those involved in multiple vehicle accidents, but confidence intervals were wider.
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Opioid Deaths in Rural Virginia: A Description of the High Prevalence of Accidental Fatalities Involving Prescribed Medications

TL;DR: In rural Virginia, drug overdose deaths increased 300% from 1997 to 2003, and polydrug deaths predominate in this review of 893 medical examiner cases, suggesting the need for different strategies in prevention, treatment, and intervention by clinicians and policymakers.
References
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Book

Disposition of Toxic Drugs and Chemicals in Man

TL;DR: Jede Substanz bildet in alphabetischer Reihenfolge der internationalen Freinamen oder chemischen Bezeichnung ein eigenes einbis dreiseitiges Kapitel mit einheitlicher Gliederung.
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Potential problems with the interpretation of hair analysis results.

TL;DR: A suitable cut-off level related to the LOD will allow correct identification of drugs or metabolites in hair and little information is available at this time to what extent test results are comparable and their interpretation is consistent.
Journal ArticleDOI

Cannabis: pharmacology and toxicology in animals and humans.

TL;DR: The advent of highly potent analogs and a specific antagonist may make possible the development of compounds that lack undesirable side effects, thus limiting therapeutic usefulness of cannabinoid-derived drugs on the market today.
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The involvement of drugs in drivers of motor vehicles killed in australian road traffic crashes

TL;DR: There were non-significant, weakly positive associations of opiates and benzodiazepines with culpability, and drivers showing the highest culpability rates were in the under 25 and over 65 age groups.
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Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment

TL;DR: It is suggested that the commonly used experimental one-day methamphetamine dosing regimen better models the acute overdose pathologies seen in humans, whereas chronic models are needed to accurately model human long-term abuse.
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