Predicting Malignancy in a Solitary Thyroid Nodule: A Prospective Study on the Role of Color Doppler Ultrasonography
Gururaja Rao,Shilpa Rao,Ravi Gopal Varma,Nikhil M Bhagwat,Manoj Chadha,Ameya Joshi,Premlata K Varthakavi +6 more
- Vol. 6, Iss: 1, pp 9-14
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TLDR
A study from a hospital from Indian west coast shows that vascular flow pattern of extensive peripheral and central flow or a central flow only and a resistive index of >0.75 on power Doppler sonography shows a healthy sensitivity and excellent specificity for pre dicting malignancy.Abstract:
Palpable thyroid nodules are fairly common. While many are benign, the clinician faces the challenge of detecting the 4 to 14% of malignant lesions. Fine needle aspiration cyto logy (FNAC) of thyroid nodules seems to have eclipsed all other techniques for diagnosis of thyroid cancer, but has its limi tations when a nodule is inaccessible or in the case of folli cular neoplasm. This study from a hospital from Indian west coast shows that vascular flow pattern of extensive peripheral and central flow (Type-3) or a central flow only (Type-4) and a resistive index (RI) of >0.75 on power Doppler sonography shows a healthy sensitivity and excellent specificity for pre dicting malignancy. The utility becomes even more apparent among follicular neoplasms where FNAC can offer little help in distinguishing malignancy.read more
Citations
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Color Doppler ultrasonography diagnostic value in detection of malignant nodules in cysts with pathologically proven thyroid malignancy: a systematic review and meta-analysis.
TL;DR: Color Doppler is a valuable non-invasive method for evaluating thyroid nodules, and it is a high-sensitivity diagnostic tool for assessing thyroid nodule sensitivity and specificity and should be included in the standard clinical protocol.
References
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TL;DR: An ultrasound examination was performed of the normal thyroid in 300 patients and small echoic nodules were demonstrated in 19% of the patients and fluid-filled masses in 6%.
Journal ArticleDOI
Power Doppler Improves the Diagnostic Accuracy of Color Doppler Ultrasonography in Cold Thyroid Nodules: Follow-Up Results
G. Cerbone,Stefano Spiezia,A. Colao,A. Di Sarno,A. P. Assanti,Rosa Lucci,M. Siciliani,G. Lombardi,G. Fenzi +8 more
TL;DR: In the current series including 322 thyroid nodules characterized by a low or absent uptake of 99mTc-pertechnetate, PD seems to provide a better characterization of thyroid nodule, possibly allowing a more accurate selection of the patients to subject to fine-needle biopsy.
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Color Doppler sonography: Anatomic and physiologic assessment of the thyroid
TL;DR: It is suggested that color Doppler sonography plays only a limited role in the evaluation of nodular thyroid disease at this time, and fine‐needle aspiration biopsy remains the most accurate method in differentiating benign and malignant lesions.
Journal ArticleDOI
High-resolution thyroid ultrasound: the value of color Doppler
TL;DR: The thyroid ultrasound is now used not only for volume determination and detection of thyroid nodules but also for characterization of nodules as benign, malignant, or dubious, being able to predict cancer with 75% accuracy.