Predictive, personalized, preventive, participatory (P4) cancer medicine
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...Further motivated by P4 (predictive, personalized, preventive, participatory) medicine [120], bioinformatics aims to predict and prevent diseases by involving patients in the development of more efficient and personalized treatments....
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1,046 citations
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...The biological network paradigm has been used to facilitate drug target selection, interpret drug resistance or offtarget effects, and forms the basis for targeted therapies and personalized medicine (14,15)....
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...Here, toolsets are urgently needed to support the bidirectional interaction with computational multiscale analysis and modelling to help to go towards the far-off goal of future medicine7 (Hood and Friend, 2011; Tian et al., 2012)....
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...ew insights. Here, toolsets are urgently needed to support the bidirectional interaction with computational multiscale analysis and modelling to help to go towards the far-o goal of future medicine7 (Hood and Friend, 2011; Tian et al., 2012). 6. Explainable Models for Text Text is inherently dierent from continuous data such as images since it is composed of (natural language) symbols used for communication between h...
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References
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"Predictive, personalized, preventiv..." refers background in this paper
...The use of trastuzumab in HER2-positive breast cancer patients is an excellent example of the effectiveness of this approach...
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"Predictive, personalized, preventiv..." refers background in this paper
...One should also point out that the germline DNA sequence of an individual is markedly different from the heterogeneous somatic genome sequences of cancer cells owing to the high mutation rates in neoplastic cells—hence cancer genomes must be distinguished from germline genomes...
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