Prevalence of autoantibody responses in acute coronavirus disease 2019 (COVID-19).
L. Angelica Lerma,Anu Chaudhary,Andrew Bryan,Chihiro Morishima,Mark H. Wener,Susan L. Fink +5 more
- Vol. 3, pp 100073-100073
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TLDR
The results suggest that acute COVID-19 is not associated with a high prevalence of clinically significant autoantibody responses of the type usually associated with autoimmune rheumatic disease, and strongly reactive antibodies to nuclear antigens are identified only in patients with a prior history of autoimmune disease.Citations
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Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
Benjamin T. Bradley,Heather Maioli,Robert Johnston,Irfan Chaudhry,Susan L. Fink,Haodong Xu,Behzad Najafian,Gail H. Deutsch,J Matthew Lacy,Timothy L. Williams,Nicole A. Yarid,Desiree A. Marshall +11 more
TL;DR: A clinicopathological report of severe COVID-19 cases by documenting histopathological changes and evidence of SARS-CoV-2 tissue tropism is provided.
Journal ArticleDOI
COVID-19 convalescent plasma composition and immunological effects in severe patients.
Yeny Acosta-Ampudia,Diana M. Monsalve,Manuel Rojas,Yhojan Rodríguez,Juan E. Gallo,J.C. Salazar-Uribe,María José Santander,Mónica P. Cala,Wildeman Zapata,María Isabel Zapata,Rubén Manrique,Juan Mauricio Pardo-Oviedo,Bernardo Camacho,Carolina Ramírez-Santana,Juan-Manuel Anaya +14 more
TL;DR: In this paper, the authors evaluated the effect of convalescent plasma (CP) on the immune response of COVID-19 patients and found that CP induced an early but transient cytokine profile modification and increases IgG anti-S1-SARS-CoV-2 antibodies.
Journal ArticleDOI
COVID-19 and the clinical course of rheumatic manifestations.
TL;DR: The manifestations of COVID-19 have been evolving over time as discussed by the authors, and various post-COVID19 syndromes are being recognised, including reactive arthritis and connective tissue disorders such as lupus and inflammatory myositis.
Journal ArticleDOI
Latent Rheumatic, Thyroid and Phospholipid Autoimmunity in Hospitalized Patients with COVID-19.
Juan-Manuel Anaya,Diana M. Monsalve,Manuel Rojas,Yhojan Rodríguez,Norma Montoya-García,Laura Milena Mancera-Navarro,Ana María Villadiego-Santana,Giovanni Rodríguez-Leguizamón,Yeny Acosta-Ampudia,Carolina Ramírez-Santana +9 more
TL;DR: It is suggested that latent autoimmunity influences the severity of COVID-19, and support further post-COVID studies in order to evaluate the development of overt autoim immune responses.
Journal ArticleDOI
COVID-19 and Antiphospholipid Antibodies: Time for a Reality Check?
TL;DR: In this article, a review of the literature on antiphospholipid antibodies (aPL) and COVID-19 patients is presented, focusing on the so-called solid phase identifiable aPL, such as aCL and aβ2GPI, but also reflect on noncriteria aPL.
References
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Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).
Spiros Miyakis,Michael D. Lockshin,Tatsuya Atsumi,D W Branch,Robin L. Brey,Ricard Cervera,R. H. W. M. Derksen,P. G. De Groot,Takao Koike,Pier Luigi Meroni,Guido Reber,Yehuda Shoenfeld,Angela Tincani,Panayiotis G. Vlachoyiannopoulos,Steven A. Krilis +14 more
TL;DR: This document appraise the existing evidence on clinical and laboratory features of APS addressed during the forum and proposes amendments to the Sapporo criteria, including definitions on features ofAPS that were not included in the updated criteria.
Journal ArticleDOI
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
Alexander E. Gorbalenya,Susan C. Baker,Ralph S. Baric,Raoul J. de Groot,Christian Drosten,Anastasia A. Gulyaeva,Bart L. Haagmans,Chris Lauber,Andrey M. Leontovich,Benjamin W. Neuman,Dmitry Penzar,Stanley Perlman,Leo L.M. Poon,Dmitry V. Samborskiy,Igor A. Sidorov,Isabel Sola,John Ziebuhr +16 more
TL;DR: The independent zoonotic transmission of SARS-CoV and SARS -CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance.
Journal ArticleDOI
Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19.
Yan Zhang,Meng Xiao,Shulan Zhang,Peng Xia,Wei Cao,Wei Jiang,Huan Chen,Xin Ding,Hua Zhao,Hongmin Zhang,Chunyao Wang,Jing Zhao,Xuefeng Sun,Ran Tian,Wei Wu,Dong Wu,Jie Ma,Yu Chen,Dong Zhang,Jing Xie,Xiaowei Yan,Xiang Zhou,Zhengyin Liu,Jinglan Wang,Bin Du,Yan Qin,Peng Gao,Xuzhen Qin,Yingchun Xu,Wen Zhang,Taisheng Li,Fengchun Zhang,Yongqiang Zhao,Yongzhe Li,Shuyang Zhang +34 more
TL;DR: A 69-year-old man with Covid-19 diagnosed in January 2020 in Wuhan, China, along with two other critically ill patients with Covod-19 who were also seen in the same intensive care unit are described.
Book ChapterDOI
Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology
TL;DR: One of the purposes of this chapter is to show that the new molecular biology of cellular antigens and auto-antibodies could now be providing insights into comprehending some features of autoimmunity.
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