Journal ArticleDOI
Prevalence of psychoactive drug use among drivers in Thailand: A roadside survey
Atiporn Ingsathit,Patarawan Woratanarat,Tongtavuch Anukarahanonta,Sasivimol Rattanasiri,Porntip Chatchaipun,Kanokporn Wattayakorn,Stephen S Lim,Paibul Suriyawongpaisal +7 more
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TLDR
The prevalence of psychoactive drug use among drivers not involved in road crashes in Thailand was not as low as an earlier study in Europe using objective measurements, particularly among commercial drivers, but for illicit drugs, the prevalence detected in this study was lower than those of earlier studies from high-income countries.About:
This article is published in Accident Analysis & Prevention.The article was published on 2009-05-01. It has received 58 citations till now. The article focuses on the topics: Psychoactive drug.read more
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From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction.
Zurina Hassan,Mustapha Muzaimi,V. Navaratnam,Nurul H.M. Yusoff,Farah Wahida Suhaimi,Rajakumar Vadivelu,Balasingam Vicknasingam,Davide Amato,Stephan von Hörsten,Nurul Iman W. Ismail,Nanthini Jayabalan,Ammar Imad Hazim,Sharif Mahsufi Mansor,Christian P. Müller +13 more
TL;DR: In this paper, the authors reviewed the available evidence and identified future research needs and found that mitragynine and M. speciosa preparations are systematically consumed with rather well defined instrumentalization goals, e.g. to enhance tolerance for hard work or as a substitute in the self-treatment of opiate addiction.
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Following “the Roots” of Kratom (Mitragyna speciosa): The Evolution of an Enhancer from a Traditional Use to Increase Work and Productivity in Southeast Asia to a Recreational Psychoactive Drug in Western Countries
Eduardo Cinosi,Giovanni Martinotti,Pierluigi Simonato,Darshan Singh,Zsolt Demetrovics,Andres Roman-Urrestarazu,Francesco Saverio Bersani,Balasingam Vicknasingam,Giulia Piazzon,Jih-Heng Li,Wen Jing Yu,Máté Kapitány-Fövény,Judit Farkas,Massimo Di Giannantonio,Ornella Corazza +14 more
TL;DR: It is concluded that the use of kratom is not negligible, especially for self-medication, and more clinical, pharmacological, and socioanthropological studies as well as a better international collaboration are needed to tackle this marginally explored phenomenon.
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The pharmacology and toxicology of kratom: from traditional herb to drug of abuse
TL;DR: There are currently no standard analytical screening techniques for mitragynine and its metabolites following ingestion limiting its detection to more sophisticated techniques like liquid chromatography-mass spectrometry to determine kratom use.
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Abuse potential and adverse cognitive effects of mitragynine (kratom)
Nurul H.M. Yusoff,Farah Wahida Suhaimi,Raja Vadivelu,Raja Vadivelu,Zurina Hassan,Anne Rümler,Andrea Rotter,Davide Amato,Hans C. Dringenberg,Sharif Mahsufi Mansor,V. Navaratnam,Christian P. Müller +11 more
TL;DR: Findings provide evidence for an addiction potential with cognitive impairments for mitragynine, which suggest its classification as a harmful drug.
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Hepatotoxicity Induced by "the 3Ks": Kava, Kratom and Khat.
Flaminia Pantano,Roberta Tittarelli,Giulio Mannocchi,Simona Zaami,Serafino Ricci,Raffaele Giorgetti,Daniela Terranova,Francesco Paolo Busardò,Enrico Marinelli +8 more
TL;DR: The aim of this review is to focus on the different patterns and the mechanisms of hepatotoxicity induced by “the 3Ks”, while trying to clarify the numerous aspects that still need to be addressed.
References
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Projections of Global Mortality and Burden of Disease from 2002 to 2030
Colin Mathers,Dejan Loncar +1 more
TL;DR: These projections represent a set of three visions of the future for population health, based on certain explicit assumptions, which enable us to appreciate better the implications for health and health policy of currently observed trends, and the likely impact of fairly certain future trends.
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Association of road-traffic accidents with benzodiazepine use
Fabio Barbone,Fabio Barbone,AD McMahon,P. G. Davey,Andrew D. Morris,Ian C. Reid,Denis G. McDevitt,Thomas M. MacDonald +7 more
TL;DR: Users of anxiolytic benzodiazepines and zopiclone were at increased risk of experiencing a road-traffic accident and should be advised not to drive.
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A review of drug use and driving: epidemiology, impairment, risk factors and risk perceptions
TL;DR: It is concluded that drug driving is a significant problem, both in terms of a general public health issue and as a specific concern for drug users.
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Psychoactive substance use and the risk of motor vehicle accidents
Kris L. L. Movig,M. P. M. Mathijssen,P.h.a. Nagel,T. van Egmond,J. De Gier,Hubert G. M. Leufkens,Antoine C. G. Egberts +6 more
TL;DR: It is concluded that drug use, especially alcohol, benzodiazepines and multiple drug use and drug-alcohol combinations, among vehicle drivers increases the risk for a road trauma accident requiring hospitalisation.
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Oral fluid testing for driving under the influence of drugs: history, recent progress and remaining challenges
TL;DR: The use of saliva as a matrix for screening or confirmation of drugs in oral fluid has been studied in a number of countries, such as the UK and the US as discussed by the authors, where the main advantages of saliva/oral fluid are the possibility for non-medical personnel to collect it without embarrassment and a better correlation between presence of drugs and impairment.