Journal ArticleDOI
Preventing a first episode of psychosis: Meta-analysis of randomized controlled prevention trials of 12 month and longer-term follow-ups
Mark van der Gaag,Filip Smit,Andreas Bechdolf,Paul French,Don H. Linszen,Alison R. Yung,Alison R. Yung,Patrick D. McGorry,Pim Cuijpers +8 more
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TLDR
A meta-analysis can demonstrate the effectiveness of the efforts to prevent or postpone a first episode of psychosis and Integrated psychological interventions need replication with more methodologically sound studies.About:
This article is published in Schizophrenia Research.The article was published on 2013-09-01. It has received 335 citations till now. The article focuses on the topics: Number needed to treat & First episode.read more
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Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders
Cherrie Galletly,David J. Castle,Frances Dark,Verity Humberstone,Assen Jablensky,Eoin Killackey,Jayashri Kulkarni,Patrick D. McGorry,Olav Nielssen,Nga Tran +9 more
TL;DR: This guideline takes a holistic approach, addressing all aspects of the care of people with schizophrenia and related disorders, not only correct diagnosis and symptom relief but also optimal recovery of social function, and uses a clinical staging model as a framework for recommendations regarding assessment, treatment and ongoing care.
Journal ArticleDOI
EPA guidance on the early intervention in clinical high risk states of psychoses.
Frauke Schultze-Lutter,Chantal Michel,Stefanie Julia Schmidt,Benno Karl Edgar Schimmelmann,Nadja P. Maric,Raimo K. R. Salokangas,Anita Riecher-Rössler,M. van der Gaag,Merete Nordentoft,Andrea Raballo,Anna Meneghelli,Max Marshall,Anthony P. Morrison,Stephan Ruhrmann,Joachim Klosterkötter +14 more
TL;DR: In this article, the authors provided evidence-based recommendations on early intervention in clinical high risk (CHR) states of psychosis, assessed according to the EPA guidance on early detection, derived from a meta-analysis of current empirical evidence on the efficacy of psychological and pharmacological interventions in CHR samples.
Journal ArticleDOI
An Individualized Risk Calculator for Research in Prodromal Psychosis
Tyrone D. Cannon,Changhong Yu,Jean Addington,Carrie E. Bearden,Kristin S. Cadenhead,Barbara A. Cornblatt,Robert K. Heinssen,Clark D. Jeffries,Daniel H. Mathalon,Thomas H. McGlashan,Diana O. Perkins,Larry J. Seidman,Ming T. Tsuang,Elaine F. Walker,Scott W. Woods,Michael W. Kattan +15 more
TL;DR: A risk calculator comparable in accuracy to those for cardiovascular disease and cancer is available to predict individualized conversion risks in newly ascertained clinical high-risk cases.
Journal ArticleDOI
Altering the course of schizophrenia: progress and perspectives
Millan Mark,Annie Andrieux,George Bartzokis,Kristin S. Cadenhead,Paola Dazzan,Paolo Fusar-Poli,Jürgen Gallinat,Jay N. Giedd,Dennis R. Grayson,Markus Heinrichs,René S. Kahn,Marie-Odile Krebs,Marion Leboyer,David A. Lewis,Oscar Marín,Philippe Marin,Andreas Meyer-Lindenberg,Patrick D. McGorry,Philip McGuire,Michael John Owen,Paul Patterson,Akira Sawa,Michael Spedding,Peter J. Uhlhaas,Flora M. Vaccarino,Claes Wahlestedt,Daniel R. Weinberger +26 more
TL;DR: A broad-based consideration of the challenges and opportunities inherent in efforts to alter the course of schizophrenia is provided, including 'hybrid' strategies that both relieve presenting symptoms and reduce the risk of transition to schizophrenia or another psychiatric disorder.
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The Lancet Psychiatry Commission on psychological treatments research in tomorrow's science
Emily A. Holmes,Ata Ghaderi,Catherine J. Harmer,Catherine J. Harmer,Paul Ramchandani,Pim Cuijpers,Anthony P. Morrison,Jonathan P. Roiser,Claudi L H Bockting,Rory C. O'Connor,Roz Shafran,Michelle L. Moulds,Michelle G. Craske +12 more
TL;DR: This Commission proposes opportunities to improve training in interdisciplinary mental health sciences, and outlines an area in which it sees substantial opportunity and scope for advancements that will move psychological treatments research forward.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Meta-Analysis in Clinical Trials*
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
Book
Statistical Methods for Meta-Analysis
Larry V. Hedges,Ingram Olkin +1 more
TL;DR: In this article, the authors present a model for estimating the effect size from a series of experiments using a fixed effect model and a general linear model, and combine these two models to estimate the effect magnitude.
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