Production of phenolic compounds from Spirulina maxima microalgae and its protective effects
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In this article, the enhancing process of phenolics synthesis in Spirulina maxima grown in Zarrouk's medium supplemented with different concentration of NaNO3 and/or combined with phenylalanine (L-PA).Abstract:
The purpose of this study was to illustrate the enhancing process of phenolics synthesis in Spirulina maxima grown in Zarrouk’s medium supplemented with different concentration of NaNO3 and/or combined with phenylalanine (L-PA). Also, the protective efficacy of Spirulina polyphenolic (SPP) extracts against CCI4-induced microsomal lipid peroxidation and scavenging of hydroxyl radical formation were performed. The results revealed that the levels of NaNO3 and L-PA in growth medium had positive effects on the production of biomass (34-64 mg/day), total phenolics (4.51-16.96 mg/g d.w) and flavonoids (1.32-5.12 mg/g d.w) contents. The highest levels of these compounds were obtained in Zarrouk’s medium containing 3.77 g/L NaNO3 and 100 mg/L L-PA. The HPLC-DAD profile of all phenolic extracts of Spirulina showed the presence of large numbers of phenolic acids and flavonoids, in variable levels. Gallic, chlorogenic, cinnamic, pinostrobin and p-OH-benzoic were found as the most abundant constituents among different extracts. Polyphenolic of Spirulina exhibited antioxidant effects CCI4-induced lipid peroxidation (inhibition %) in liver homogenate and on DPPH radical scavenging activity (with IC50 values ranged from 23.22 to 35.62 ig/ml), in dose-depended manner. Their protective potential was comparable to that of standard phenolic antioxidants (BHT, BHA and -tocopherol, with IC50 values ranged from 13.22 to 23.62 ig/ml). Thus, S. maxima can be regarded as potent natural sources of nutraceutical and functional ingredients.read more
Citations
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TL;DR: Microalgae can be regarded as an alternative and promising food ingredient due to their nutritional composition, richness in bioactive compounds, and because they are considered a sustainable protein source for the future.
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Therapeutic Potentials of Microalgae in the Treatment of Alzheimer's Disease.
TL;DR: The antioxidant, anticholinesterase activities as well as the inhibitory effects of some bioactive compounds from microalgae extracts on β-amyloid aggregation and neuronal death are discussed extensively.
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Functional characters evaluation of biscuits sublimated with pure phycocyanin isolated from Spirulina and Spirulina biomass
TL;DR: It could be concluded that functional biscuits had good sensory and nutritional profiles and can be developed as new niche food market.
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Anticancer effect of the water extract of a commercial Spirulina (Arthrospira platensis) product on the human lung cancer A549 cell line.
Arkadiusz Czerwonka,Katarzyna Kaławaj,Adrianna Sławińska-Brych,Marta Kinga Lemieszek,Magdalena Bartnik,Krzysztof Kamil Wojtanowski,Barbara Zdzisińska,Wojciech Rzeski +7 more
TL;DR: Evidence of the anti-cancer activity of the commercial Spirulina product against lung cancer cells is provided and the knowledge of the chemopreventive properties of Spiruline is strongly supported.
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Antioxidant activity of the microalga Spirulina maxima
TL;DR: The results obtained indicate that Spirulina provides some antioxidant protection for both in vitro and in vivo systems.
Journal ArticleDOI
Antioxidant effectiveness of selected wines in comparison with (+)-catechin
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Production of biomass and nutraceutical compounds by Spirulina platensis under different temperature and nitrogen regimes.
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TL;DR: It is found that at 35 degrees C there was a negative effect on biomass production but a positive effect on the production of protein, lipids and phenolics, and at 30 degrees C the concentration of sodium nitrate in Zarrouk's medium can be reduced without loss of productivity, an important cost-saving factor in large-scale cultivation.