Prognosis of Women With Metastatic Breast Cancer by HER2 Status and Trastuzumab Treatment: An Institutional-Based Review
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2,862 citations
Cites background from "Prognosis of Women With Metastatic ..."
...Biologic agent other than trastuzumab or pertuzumab 21 (4) 13 (3)...
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1,413 citations
Cites background from "Prognosis of Women With Metastatic ..."
...High HER2 expression was first a marker of worse survival, but the introduction of targeted anti-HER2 therapy changed the picture: today HER2 positive patients have an improved prognosis compared to women with HER2 negative disease [27]....
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Cites background from "Prognosis of Women With Metastatic ..."
...receptor 2 (HER2) occurs in 15% to 25% of all breast cancers and is associated with poor prognosis.(1,2) The...
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References
14,768 citations
"Prognosis of Women With Metastatic ..." refers background in this paper
...Gene expression profiling has identified up to six molecular subtypes that are based on both hormone receptor and HER2/neu status of tumors.(16) In a cohort of 49 women with locally advanced breast cancer, Sørlie et al(17) reported that OS and relapse-free survival were the poorest for patients with the basal-like and HER2/ neu-positive breast tumor subtypes compared with women with luminal breast tumor subtypes....
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11,597 citations
"Prognosis of Women With Metastatic ..." refers background in this paper
...detected at abnormally high levels in these malignant cells.(2,3) Its main function is to mediate growth,...
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...survival (OS) compared with women whose tumors do not over express HER2/neu.(2-4)...
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10,791 citations
10,532 citations
"Prognosis of Women With Metastatic ..." refers background in this paper
...with metastatic HER2/neu-positive breast cancer.(5) After these findings, large randomized clini-...
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6,938 citations
"Prognosis of Women With Metastatic ..." refers background in this paper
...detected at abnormally high levels in these malignant cells.(2,3) Its main function is to mediate growth,...
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...survival (OS) compared with women whose tumors do not over express HER2/neu.(2-4)...
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