Protection from H1N1 influenza virus infections in mice by supplementation with selenium: a comparison with selenium-deficient mice.
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Cites background from "Protection from H1N1 influenza viru..."
...5 mg Se⋅kg−1, and mice with low serum selenium concentrations showed a marked reduction in body weight (BW) and lower levels of TNF-α and IFN-γ.(120) For improving the immune response in the body, the administration of SeNPs can also be an efficient realizable approach....
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...The mortality of the H1N1 influenza virus-infected selenium-deficient mice was 3 times higher compared to those receiving Na 2 SeO 3 at the dose of 0.5 mg Se⋅kg−1, and mice with low serum selenium concentrations showed a marked reduction in body weight (BW) and lower levels of TNF-α and IFN-γ.120 For improving the immune response in the body, the administration of SeNPs can also be an efficient realizable approach....
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297 citations
Cites background from "Protection from H1N1 influenza viru..."
...↓ GPX activity in infected people [116] AM = KunMing Mice SS = Selenite Reduces mortality, ↑ levels of TNFalpha and IFNgamma No change in viral load [197]...
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272 citations
Cites background from "Protection from H1N1 influenza viru..."
...Though Se supplementation did not decrease the viral titer, it achieved 50 % reduction of mortality as compared to virus-infected Se-deficient mice, hence providing some evidence that Se supplementation improves the immune response to lethal influenza infection [165]....
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216 citations
References
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"Protection from H1N1 influenza viru..." refers background in this paper
...Barnard DL reported that the prophylactic use of ZnAL42 is effective against avian influenza H5N1 or H1N1 virus infection in mice [6]....
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