Protective and pathological roles of mast cells and basophils
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...and helminth-killing toxins that, however, also cause significant problems of itching, redness, swelling, and altered function of the entire organ (Pulendran and Artis, 2012; Voehringer, 2013)....
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...…M2) macrophages that together release beneficial pro-inflammatory mediators, toxin-neutralizing enzymes, and helminth-killing toxins that, however, also cause significant problems of itching, redness, swelling, and altered function of the entire organ (Pulendran and Artis, 2012; Voehringer, 2013)....
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...The most important effector cells involved in anaphylaxis are mast cells, but basophils, neutrophils, monocytes, macrophages, and platelets have also been implicated.(118,121) Histamine is an important mediator of anaphylaxis, and studies have demonstrated that intravenous histamine can induce symptoms of anaphylaxis, including flushing, airway obstruction, systemic hypotension, and tachycardia....
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...POTENTIAL EFFECTOR CELLS OF ANAPHYLAXIS Mast cells Mast cells are viewed as key players in IgE-dependent allergies and anaphylaxis.(15,128) Mast cells ordinarily express large numbers of the high-affinity IgE receptor FcεRI....
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