Protective effect of porcine placenta in a menopausal ovariectomized mouse.
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"Protective effect of porcine placen..." refers background in this paper
...Estrogen exerts its effects by binding to ERs and modulating the transcription of target genes including growth factors (Heldring et al. 2007)....
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"Protective effect of porcine placen..." refers background in this paper
...In osteoblasts, mitogen-activated protein kinase is also rapidly activated by E2, which may be involved in the proliferative and bone protective effects (Kousteni et al. 2001)....
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1,201 citations
"Protective effect of porcine placen..." refers background in this paper
...Estrogen regulates a number of physiological processes in ER-positive breast cancer cells, including proliferation (Hall et al. 2001)....
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...E2-ER complexes bind to ERE in target promoters leading to the regulation of gene transcription and subsequent tissue responses such as cell proliferation (Hall et al. 2001)....
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831 citations
"Protective effect of porcine placen..." refers background in this paper
...The menopause leads to typical menopausal symptoms such as insomnia, vaginal dryness, hot flushes, or night sweats (Dennerstein et al. 2000)....
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