Protein export through the bacterial Sec pathway
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Cites background from "Protein export through the bacteria..."
...The proteins may contain a SecB-specific signal sequence for transport to the periplasm or the extracellular milieu; however, if it has the signal recognition particle (SRP) signal it can follow the SRP pathway and remain in the inner membrane (Green and Mecsas, 2016; Tsirigotaki et al., 2017)....
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Cites background from "Protein export through the bacteria..."
...1a) is the most important transport route for proteins that are exported out of the cytosol [11]....
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140 citations
Cites background from "Protein export through the bacteria..."
..., proteins to be secreted are first carried across the inner membrane (IM) and into the periplasm by the Sec translocon (7) or Tat pathway (8) and then, after folding into a tertiary conformation (and in some instances, undergoing oligomerization), are transported across the outer membrane (OM) by the dedicated T2S apparatus (2)....
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References
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