Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination
Citations
47 citations
Cites background or methods from "Pulmonary carcinosarcoma initially ..."
...The incidence of respiratory failure is significant after inhalational injuries, with hypoxemia, pneumonia, and respiratory failure with prolonged ventilatory support and extended hospitalizations being common [1-4]....
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...Table 2 Groups of patients graded according to depth of mucosal damage estimated by fiberoptic bronchoscopy on admission, in line with Chou’s classification [3]...
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28 citations
27 citations
Cites background from "Pulmonary carcinosarcoma initially ..."
...A review of the literature revealed 35 cases of noncarcinoid primary lung carcinomas with coexisting Aspergillus at the time of the initial diagnosis (Table 2A-D) [9-39], about half of them in nonEnglish journals....
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...There are also scattered case reports of aspergillosis associated with pulmonary carcinomas at the time of primary diagnosis including 4 carcinoid tumors [5-39]....
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22 citations
Cites background from "Pulmonary carcinosarcoma initially ..."
...When heterologous sarcoma elements such as cartilage or skeletal muscle are present, it is easier to confirm the biphasic nature of the tumor, although immunostains can be of further help such as Myogenin and Myo D1 for rhabdomyosarcoma, smooth muscle actin and desmin for leiomyosarcoma, and S100 for chondrosarcoma (3)....
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...Pulmonary carcinosarcoma is a rare and highly malignant lung neoplasm characterized by a biphasic histopathological pattern consisting of both epithelial and sarcomatous components (1-6)....
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...Diaconita reported eight cases among 3,000 patients with malignant pulmonary tumors (3)....
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...Biopsy of the tumor, especially when centrally located, often shows only one component, and peripheral tumors are difficult to reach endoscopically (3,6,7)....
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...More than 90% of the patients have a history of heavy smoking (3)....
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20 citations
References
2,314 citations
"Pulmonary carcinosarcoma initially ..." refers methods in this paper
...In retrospective microbiology studies of patients with “proven” and “probable” invasive aspergillosis based on the European Organization for Research and Treatment of Cancer, and the Mycosis Study Group of the National Institute of Allergy and Infectious Diseases criteria between 1993-2003, only 1 of a total of 13 patients who met the criteria for invasive aspergillosis was found to have lung cancer [10-12]....
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1,858 citations
504 citations
"Pulmonary carcinosarcoma initially ..." refers result in this paper
...The typical tissue reaction in aspergillus pneumonia is known to be hemorrhagic infarction with a sparse inflammatory infiltrate [13], and our case revealed similar features....
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306 citations
"Pulmonary carcinosarcoma initially ..." refers background or methods in this paper
...In retrospective microbiology studies of patients with “proven” and “probable” invasive aspergillosis based on the European Organization for Research and Treatment of Cancer, and the Mycosis Study Group of the National Institute of Allergy and Infectious Diseases criteria between 1993-2003, only 1 of a total of 13 patients who met the criteria for invasive aspergillosis was found to have lung cancer [10-12]....
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...renal impairment, low monocyte counts, disseminated aspergillosis, diffuse pulmonary lesions, pleural effusion, and proven or probable aspergillosis [11]....
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303 citations
"Pulmonary carcinosarcoma initially ..." refers background in this paper
...It most often presents as aspergillus pneumonia and almost always involves immunoecompromized or debilitated patients with underlying malignancy [9]....
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...Risk factors include prolonged and severe neutropenia, hematopoietic stem cell and solid organ transplantation, advanced AIDS, and chronic granulomatous disease [9]....
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