Pulmonary cryptococcosis induces chitinase in the rat.
Citations
12 citations
Cites background from "Pulmonary cryptococcosis induces ch..."
...The presence of bacterial chitinases in human colon can play an important role as part of defence mechanisms against fungal invasion (Vicencio et al., 2008)....
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12 citations
11 citations
Cites background from "Pulmonary cryptococcosis induces ch..."
...In addition, the immunological roles of host mammalian chitinases have also recently been evaluated in various inflammatory disease models including asthma or allergen challenge with ovalbumin, Th2- and IL13-mediated inflammation, cigarette smoke challenge models, and pulmonary cryptococcosis [38, 39]....
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10 citations
10 citations
Cites background from "Pulmonary cryptococcosis induces ch..."
...Similarly, six chitinases from Bacillus circulans WL-12 were reported by Watanabe et al. (1992) Members of the genus Bacillus are well known for their potential to secrete a number of degradative enzymes such as chitinases (Schallmey et al., 2004)....
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References
795 citations
"Pulmonary cryptococcosis induces ch..." refers background or methods or result in this paper
...Acidic mammalian chitinase (AMCase) has emerged as an important mediator of allergic asthma in both animal models and in humans [5-7]....
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...Evidence from their laboratory demonstrates that over-expression of IL-13 induces endogenous AMCase activity and results in airway hyperreactivity [5], and that blockage of AMCase activity attenuates the response....
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...that increased AMCase expression in airway epithelial cells and alveolar macrophages parallels generalized chitinase activity and is consistent with previous investigations [5,13]....
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...Chitinase activity assay was performed utilizing an established protocol [5]....
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525 citations
"Pulmonary cryptococcosis induces ch..." refers background in this paper
...Importantly, additional proteins with chitinase activity have also been discovered in both rodents and humans, including BRP-39 (mouse), YKL-40 (human) and chitotriosidase [17]....
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489 citations
"Pulmonary cryptococcosis induces ch..." refers methods in this paper
...Reactivity at 50 kDa, the approximate molecular weight of AMCase, was used to indicate AMCase expression [9]....
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382 citations
"Pulmonary cryptococcosis induces ch..." refers background in this paper
...neoformans infection is common among Bronx children, a cohort with an extraordinarily high rate of asthma, suggesting a potential role for this type of infection in asthma pathogenesis [4]....
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328 citations
"Pulmonary cryptococcosis induces ch..." refers background in this paper
...We also note that chitin is also major constituent of other exposures that have been linked with urban asthma including cockroaches [19]....
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