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Pursuing the Diffraction Limit with Nano-LED Scanning Transmission Optical Microscopy.

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TLDR
In this article, an optically downscaled LED using an LED scanning transmission optical microscopy (STOM) technique was used to improve STOM images by oversampling the acquisition.
Abstract
Recent research into miniaturized illumination sources has prompted the development of alternative microscopy techniques. Although they are still being explored, emerging nano-light-emitting-diode (nano-LED) technologies show promise in approaching the optical resolution limit in a more feasible manner. This work presents the exploration of their capabilities with two different prototypes. In the first version, a resolution of less than 1 µm was shown thanks to a prototype based on an optically downscaled LED using an LED scanning transmission optical microscopy (STOM) technique. This research demonstrates how this technique can be used to improve STOM images by oversampling the acquisition. The second STOM-based microscope was fabricated with a 200 nm GaN LED. This demonstrates the possibilities for the miniaturization of on-chip-based microscopes.

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Journal ArticleDOI

Individually Switchable InGaN/GaN Nano-LED Arrays as Highly Resolved Illumination Engines

TL;DR: In this article, two different approaches to achieve individually switchable nano-LED arrays were evaluated in terms of near field spot size and optical crosstalk between neighboring pixels by using finite difference time domain (FDTD) simulations.
Proceedings ArticleDOI

High power and high bandwidth CMOS driver for hybrid interconnected GaN microdisplay

TL;DR: In this article , an in-pixel driving circuit with switching capabilities up to 1MHz and LED bias current up to 120µA was presented, which is designed to be integrated in a 512x512 microdisplay of 1411 ppi with 10kfps working capabilities.
Proceedings ArticleDOI

Ray Tracing Simulation of a GaN-based integrated LED-Photodetector System

TL;DR: In this paper , an optical sensor system consisting of a pair of GaN LED and Photodetector (PD) is simulated using COMSOL multiphysics, and the possibility of using this system as absorption coefficient sensor is studied.
References
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Journal ArticleDOI

Optical Constants of the Noble Metals

TL;DR: In this paper, the optical constants for the noble metals (copper, silver, and gold) from reflection and transmission measurements on vacuum-evaporated thin films at room temperature, in the spectral range 0.5-6.5 eV.
Journal ArticleDOI

Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy

TL;DR: A new type of scanning fluorescence microscope capable of resolving 35 nm in the far field is proposed, overcome the diffraction resolution limit by employing stimulated emission to inhibit the fluorescence process in the outer regions of the excitation point-spread function.
BookDOI

Handbook of biological confocal microscopy

TL;DR: Methods for Three-Dimensional Imaging and Tutorial on Practical Confocal Microscopy and Use of the Confocal Test Specimen.
Journal ArticleDOI

High-resolution quantitative phase-contrast microscopy by digital holography

TL;DR: Techniques of digital holography are improved in order to obtain high-resolution, high-fidelity images of quantitative phase-contrast microscopy, and the angular spectrum method of calculating holographic optical field is seen to have significant advantages including tight control of spurious noise components.
Journal ArticleDOI

Light-induced cell damage in live-cell super-resolution microscopy.

TL;DR: This work applied single-molecule localization microscopy conditions and tested the influence of irradiation intensity, illumination-mode, wavelength, light-dose, temperature and fluorescence labeling on the survival probability of different cell lines 20–24 hours after irradiation.
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