Journal ArticleDOI
Quantitative Analysis of Mitral Annular Geometry and Function in Healthy Volunteers Using Transthoracic Three-Dimensional Echocardiography
Sorina Mihaila,Sorina Mihaila,Denisa Muraru,Eleonora Piasentini,Marcelo Haertel Miglioranza,Diletta Peluso,Umberto Cucchini,Sabino Iliceto,Dragos Vinereanu,Luigi P. Badano +9 more
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TLDR
Three-dimensional transthoracic echocardiographic data sets acquired with current scanners have enough spatial and temporal resolution to allow the quantitative analysis of the mitral annulus, and quantitative analysis by 3D TTE in unselected patients with mitral valve disease was accurate and reproducible in healthy subjects.Abstract:
Background Quantitative assessment of the mitral annulus provides information regarding the pathophysiology of mitral regurgitation and aids in the planning of reparative surgery. Three-dimensional (3D) transthoracic echocardiographic data sets acquired with current scanners have enough spatial and temporal resolution to allow the quantitative analysis of the mitral annulus. Accordingly, the authors performed (1) a validation study to assess the agreement of quantitative analysis of the mitral annulus performed on 3D transthoracic echocardiography (TTE) and 3D transesophageal echocardiography (TEE) and (2) a normative study to obtain the reference values of 3D transthoracic echocardiographic parameters for mitral annular (MA) geometry and dynamics. Methods Mitral valve data sets were obtained by 3D TEE and 3D TTE in 30 consecutive patients with clinically indicated TEE (validation study) and 3D TTE in 224 healthy volunteers (aged 18–76 years) (normative study). Results In the validation study, MA measurements obtained by 3D TTE were similar to those obtained by 3D TEE ( P = NS). In the normative study, MA analysis by 3D TTE was feasible (94.5%) and reproducible (intraclass correlation coefficient = 0.78–0.97). MA diameters, area, and circumference were correlated with body surface area ( r > 0.50 for all) but not with age. Men had larger MA areas than women (4.9 ± 1.0 vs 4.5 ± 0.7 cm 2 /m 2 , P = .004). During systole, MA area decreased by 29 ± 5%. This decrease was related mainly to anteroposterior diameter shortening (20 ± 7%). Conclusions MA quantitative analysis by 3D TTE was accurate compared with 3D TEE in unselected patients with mitral valve disease. In healthy subjects, it was highly feasible and reproducible. The availability of reference values for MA geometry and dynamics may foster the implementation of MA quantitative analysis by 3D TTE in clinical settings.read more
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Journal ArticleDOI
Multimodality Imaging in the Context of Transcatheter Mitral Valve Replacement: Establishing Consensus Among Modalities and Disciplines.
Philipp Blanke,Christopher Naoum,John G. Webb,Danny Dvir,Rebecca T. Hahn,Paul A. Grayburn,Robert Moss,Mark Reisman,Nicolo Piazza,Jonathon Leipsic +9 more
TL;DR: An overview of anatomical principles and definitions, a methodology for anatomical quantification, and perioperative guidance are provided.
Journal ArticleDOI
Functional Regurgitation of Atrioventricular Valves and Atrial Fibrillation: An Elusive Pathophysiological Link Deserving Further Attention.
Denisa Muraru,A C Guta,Roberto C. Ochoa-Jimenez,Daniela Bartos,Patrizia Aruta,Sorina Mihaila,Bogdan A. Popescu,Sabino Iliceto,Cristina Basso,Luigi P. Badano +9 more
TL;DR: The comparative anatomy of mitral and tricuspid apparatus and the pathophysiology and typical echocardiographic features of atrial functional regurgitation compared with ventricular functional regurger are described, as well as the added value of three-dimensional echOCardiography as an essential imaging tool to clarify the mechanisms involved in its development.
Journal ArticleDOI
Mitral Annular Dimensions and Geometry in Patients With Functional Mitral Regurgitation and Mitral Valve Prolapse: Implications for Transcatheter Mitral Valve Implantation
Christopher Naoum,Jonathon Leipsic,Anson Cheung,Jian Ye,Nicolas Bilbey,George Mak,Adam C. Berger,Danny Dvir,Chesnal Arepalli,Jasmine Grewal,David W.M. Muller,Darra T. Murphy,Cameron J. Hague,Nicolo Piazza,John G. Webb,Philipp Blanke +15 more
TL;DR: Moderate to severe MR was associated with increased MA dimensions, especially among patients with MVP compared with control subjects without cardiac disease and to determine predictors of annular size, using cardiac computed tomography.
Journal Article
Abstract 3177: Saddle-shaped Mitral Valve Annuloplasty Rings Improve Leaflet Coaptation Geometry
Morten O. Jensen,Henrik Jensen,Morten Smerup,Robert A. Levine,Ajit P. Yoganathan,Hans Nygaard,J. Michael Hasenkam,Sten Lyager Nielsen +7 more
TL;DR: Saddle-shaped annuloplasty rings provide better leaflet coaptation geometry than do flat rings by not hoisting the papillary muscles toward the posterior annulus through the commissural chordae, allowing greater leaflet mobility.
Journal ArticleDOI
Physiologic Determinants of Left Atrial Longitudinal Strain: A Two-Dimensional Speckle-Tracking and Three-Dimensional Echocardiographic Study in Healthy Volunteers.
Marcelo Haertel Miglioranza,Luigi P. Badano,Sorina Mihaila,Diletta Peluso,Umberto Cucchini,Nicola Soriani,Sabino Iliceto,Denisa Muraru +7 more
TL;DR: LA LS values are different in men and women and should be interpreted taking into account patient age and LV function as well, which may help identify subclinical LA dysfunction in several cardiovascular or systemic conditions.
References
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TL;DR: Guidelines summarize and evaluate all evidence available on a particular issue with the aim of assisting physicians in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome.
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Guidelines on the management of valvular heart disease (version 2012)The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
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Patrizio Lancellotti,Christophe Tribouilloy,Andreas Hagendorff,Bogdan A. Popescu,Thor Edvardsen,Thor Edvardsen,Luc Pierard,Luigi P. Badano,José Luis Zamorano +8 more
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Journal ArticleDOI
Quantitative determinants of the outcome of asymptomatic mitral regurgitation
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TL;DR: Quantitative grading of mitral Regurgitation is a powerful predictor of the clinical outcome of asymptomatic mitral regurgitation and patients with an effective regurgitant orifice of at least 40 mm2 should promptly be considered for cardiac surgery.
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EAE/ASE Recommendations for Image Acquisition and Display Using Three-Dimensional Echocardiography
Roberto M. Lang,Luigi P. Badano,Wendy Tsang,David H. Adams,Eustachio Agricola,Thomas Buck,Francesco Faletra,Andreas Franke,Judy Hung,Leopoldo Pérez de Isla,Otto Kamp,Jarosław D. Kasprzak,Patrizio Lancellotti,Thomas H. Marwick,Marti L. McCulloch,Mark J. Monaghan,Petros Nihoyannopoulos,Natesa G. Pandian,Patricia A. Pellikka,Mauro Pepi,David A. Roberson,Stanton K. Shernan,Girish S Shirali,Lissa Sugeng,Folkert J. Ten Cate,Mani A. Vannan,José Luis Zamorano,William A. Zoghbi +27 more
TL;DR: The main goal of this document is to provide a practical guide on how to acquire, analyze, and display the various cardiac structures using 3D echocardiography, as well as limitations of the technique.
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