Journal ArticleDOI
Quantitative analysis of steroid hormones in human hair using a column-switching LC-APCI-MS/MS assay.
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TLDR
The development of a LC-MS/MS-based method for simultaneous identification of endogenous concentrations of seven steroid hormones (cortisol, cortisone, testosterone, progesterone, corticosterone, dehydroepiandrosterone (DHEA) and androstenedione) in human hair is reported.About:
This article is published in Journal of Chromatography B.The article was published on 2013-06-01. It has received 309 citations till now. The article focuses on the topics: Steroid hormone & Dehydroepiandrosterone.read more
Citations
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Journal ArticleDOI
Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples.
Michaela Breier,Simone Wahl,Cornelia Prehn,Marina Fugmann,Uta Ferrari,M Weise,F Banning,Jochen Seissler,Harald Grallert,Jerzy Adamski,Andreas Lechner +10 more
TL;DR: A single time point measurement is assumed to be sufficient for a targeted metabolomics analysis of most metabolites, and plasma and serum metabolite stability showed good coherence.
Journal ArticleDOI
Cortisol in Hair and the Metabolic Syndrome
Tobias Stalder,Clemens Kirschbaum,Nina Alexander,Stefan R. Bornstein,Wei Gao,Wei Gao,Robert Miller,Sabine Stark,Jos A. Bosch,Jos A. Bosch,Joachim E. Fischer +10 more
TL;DR: Normal physiological differences in long-term cortisol secretion, as assessed in hair, show relevant relationships with MetS and individual cardiometabolic parameters.
Journal ArticleDOI
Hair cortisol as a biomarker of traumatization in healthy individuals and posttraumatic stress disorder patients.
Susann Steudte,Clemens Kirschbaum,Wei Gao,Wei Gao,Nina Alexander,Sabine Schönfeld,Jürgen Hoyer,Tobias Stalder +7 more
TL;DR: The results indicate that trauma exposure per se, either in the absence or presence of PTSD, is a crucial correlate of long-term basal cortisol levels.
Journal ArticleDOI
Correspondence between hair cortisol concentrations and 30-day integrated daily salivary and weekly urinary cortisol measures
Sarah J. Short,Tobias Stalder,Kristine Marceau,Sonja Entringer,Nora K. Moog,Elizabeth A. Shirtcliff,Pathik D. Wadhwa,Claudia Buss,Claudia Buss +8 more
TL;DR: Findings support the contention that HCC provides a reliable estimate of long-term integrated free cortisol production that is aligned with integrated salivary cortisol production measured over a corresponding one-month period.
Journal ArticleDOI
The Lifespan Human Connectome Project in Development: A large-scale study of brain connectivity development in 5-21 year olds.
Leah H. Somerville,Susan Y. Bookheimer,Randy L. Buckner,Gregory C. Burgess,Sandra W. Curtiss,Mirella Dapretto,Jennifer Stine Elam,Michael S. Gaffrey,Michael P. Harms,Cynthia Hodge,Sridhar Kandala,Erik K. Kastman,Thomas E. Nichols,Bradley L. Schlaggar,Stephen M. Smith,Kathleen M. Thomas,Essa Yacoub,David C. Van Essen,M Deanna +18 more
TL;DR: The overarching aims of the HCP‐D are outlined, the approach taken to acquire maximally informative data while minimizing participant burden, preliminary analyses, and discussion of the intended uses and limitations of the dataset are outlined.
References
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Journal ArticleDOI
Analysis of cortisol in hair--state of the art and future directions.
TL;DR: Evidence on a recent methodological development assumed to provide a considerable advancement in the analysis of cortisol in hair is discussed, which holds great promise to significantly enhance current understanding on the role of steroid hormones in psychoimmunological research.
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Potential problems with the interpretation of hair analysis results.
TL;DR: A suitable cut-off level related to the LOD will allow correct identification of drugs or metabolites in hair and little information is available at this time to what extent test results are comparable and their interpretation is consistent.
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Measurement of cortisol in human Hair as a biomarker of systemic exposure
TL;DR: The correlation of hair cortisol with 24-hour urine cortisol supports its relevance as biomarker for long-term exposure and determines a reference range for non-obese subjects.
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Hair as a retrospective calendar of cortisol production-Increased cortisol incorporation into hair in the third trimester of pregnancy.
TL;DR: C cortisol measured in human hair can be a valid reflection of increased cortisol production for a period of up to six months, probably reflecting increased cortisol levels throughout the third trimester of pregnancy.
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Detection of physiological concentrations of cortisol and cortisone in human hair.
TL;DR: A new extraction, purification, and separation technique using liquid chromatography and mass spectrometry for the identification and quantification of two endogenous glucocorticoids: cortisol and cortisone is developed and it is found that cortis one concentrations in hair are significantly higher before the age of 20.