Quantitative determinants of the outcome of asymptomatic mitral regurgitation
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...Our knowledge of the natural history of chronic MR has greatly improved due to recent observational studies.(34,91,95,96) In asymptomatic MR, the estimated 5 year rates (+ standard error) of death from any cause, death from cardiac causes, and cardiac events (death from cardiac causes, heart failure, or new AF) with medical management were 22+ 3, 14+ 3, and 33+ 3%, respectively....
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...The two quantitative methods of evaluating regurgitant volume and calculating ERO are useful in experienced hands.(90,91) The criteria for defining severe organic MR are described in Table 2....
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...In asymptomatic MR, the estimated 5 year rates (+ standard error) of death from any cause, death from cardiac causes, and cardiac events (death from cardiac causes, heart failure, or new AF) with medical management were 22+ 3, 14+ 3, and 33+ 3%, respectively.(91) In addition to symptoms, age, atrial fibrillation, degree of MR (particularly ERO), left atrial dilatation, LV dilatation, and low LVEF are all predictors of poor outcome....
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