Journal ArticleDOI
Quantum dots: a promising tool in molecular biology
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TLDR
In this paper, the potential uses of this versatile nano crystal are discussed and toxicity issues surrounding this nano crystal and speculate about the future uses of quantum dot in large areas of biomedical sciences.Abstract:
Quantum dot is a spatial semiconductor of periodic groups of II-VI, III-V, or IV-VI materials, which generates optically stable fluorophores upon excitations at various wavelengths (from UV-IR). To date, quantum dot technologies are used in various fields and the use in molecular biology has increased dramatically over the past years. In this review article, we would discuss the potential uses of this versatile nano crystal. Quantum dot technology is also used in cell labelling, bio-sensing, in-vivo imaging, bimodal magnetic-luminescent imaging, and diagnostics. We would also discuss toxicity issues surrounding this nano crystal and speculate about the future uses of quantum dot in large areas of biomedical sciences.read more
Citations
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Quenching of Fluorescence in Bodipy‐Derived Trifluoromethyl Enaminone Ligands upon Coordination to Copper(II)
TL;DR: In this paper, two trifluoromethyl-derived enaminone ligands, L1H (bidentate) and L2H2, (tridentate), which bear a fluorescent 4,4-difluoro-4-bora-3a,4a-diaza-sindacene (Bodipy) moiety, were synthesized.
Journal ArticleDOI
Computer modeling to optimize the sensitivity of an optical DNA nanosensor
Roozbeh Hushiarian,Nor Azah Yusof,Negin Houshiarian,Abdul Halim Abdullah,Shahrul Ainliah Alang Ahmad +4 more
TL;DR: The sensitivity of an optical DNA nanosensor based on MNPs and QDs was enhanced by using computer simulations including an innovative software, Grasshopper, to better understand how they network in different concentrations of the solution.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
Xavier Michalet,Fabien Pinaud,Laurent A. Bentolila,James M. Tsay,Sören Doose,J. Jack Li,Gobalakrishnan Sundaresan,Anna M. Wu,Sanjiv S. Gambhir,Sanjiv S. Gambhir,Shimon Weiss +10 more
TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
Journal ArticleDOI
In vivo cancer targeting and imaging with semiconductor quantum dots
TL;DR: Sensitive and multicolor fluorescence imaging of cancer cells under in vivo conditions are achieved and a whole-body macro-illumination system with wavelength-resolved spectral imaging is integrated for efficient background removal and precise delineation of weak spectral signatures.
Journal ArticleDOI
(CdSe)ZnS Core-Shell Quantum Dots - Synthesis and Characterization of a Size Series of Highly Luminescent Nanocrystallites
B. O. Dabbousi,Javier Rodríguez-Viejo,F. V. Mikulec,Jason Heine,Hedi Mattoussi,R. Ober,K. F. Jensen,‡,§ and,Moungi G. Bawendi +7 more
TL;DR: In this paper, a synthesis of highly luminescent (CdSe)ZnS composite quantum dots with CdSe cores ranging in diameter from 23 to 55 A was reported.
Journal ArticleDOI
Probing the Cytotoxicity Of Semiconductor Quantum Dots.
TL;DR: This work found that CdSe-core QDs were indeed acutely toxic under certain conditions and modulated by processing parameters during synthesis, exposure to ultraviolet light, and surface coatings, and suggests that cytotoxicity correlates with the liberation of free Cd2+ ions due to deterioration of the Cd Se lattice.