Randomized Comparison of Systemic Anti-inflammatory Therapy Versus Fluocinolone Acetonide Implant for Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment Trial
John H. Kempen,Michael M. Altaweel,Janet T. Holbrook,Douglas A. Jabs,Thomas A. Louis,Elizabeth A. Sugar,Jennifer E. Thorne,Jennifer E. Thorne +7 more
Reads0
Chats0
TLDR
In each treatment group, mean visual acuity improved over 24 months, with neither approach superior to a degree detectable with the study's power, suggesting that the specific advantages and disadvantages identified should dictate selection between the alternative treatments in consideration of individual patients' particular circumstances.About:
This article is published in Ophthalmology.The article was published on 2011-10-01 and is currently open access. It has received 267 citations till now. The article focuses on the topics: Fluocinolone acetonide & Uveitis.read more
Citations
More filters
Journal ArticleDOI
Ocular Drug Delivery: Present Innovations and Future Challenges.
TL;DR: Novel drug-delivery technologies, including nanoparticles, nanomicelles, dendrimers, microneedles, liposomes, and nanowafers, are increasingly studied for anterior and posterior disorders.
Journal ArticleDOI
Risk factors for loss of visual acuity among patients with uveitis associated with juvenile idiopathic arthritis: the Systemic Immunosuppressive Therapy for Eye Diseases Study.
Anthony C. Gregory,John H. Kempen,Ebenezer Daniel,R. Oktay Kaçmaz,C. Stephen Foster,Douglas A. Jabs,Douglas A. Jabs,Grace A. Levy-Clarke,Robert B. Nussenblatt,James T. Rosenbaum,Eric B. Suhler,Eric B. Suhler,Jennifer E. Thorne,Jennifer E. Thorne +13 more
TL;DR: Ocular complications and vision loss were common in patients with juvenile idiopathic arthritis-related uveitis, and use of immunosuppressive drugs was associated with reduced risk of vision loss, suggesting that control of inflammation and Use of Immunosuppression may be critical aspects in improving the outcomes of patients with JIA-related Uveitis.
Journal ArticleDOI
Intraocular Pressure Monitoring Post Intravitreal Steroids: A Systematic Review
Weerawat Kiddee,Weerawat Kiddee,Graham E. Trope,Lisa Sheng,Laura Beltran-Agullo,Michael Smith,M. Hermina Strungaru,Jasrajbir Baath,Yvonne M. Buys +8 more
TL;DR: A protocol to monitor IOP after IVT steroid injection/implantation is suggested that includes checking IOP within 30 minutes after injection, followed by 1 week after IVt triamcinolone and 2 weeks after implant insertion, then every 2 weeks for the first month and monthly for up to 6 months after IVCtriamcinlone and dexamethasone implantation.
Journal ArticleDOI
Role of the Retinal Vascular Endothelial Cell in Ocular Disease
Arpita S. Bharadwaj,Binoy Appukuttan,Phillip A. Wilmarth,Yuzhen Pan,Andrew J. Stempel,Timothy J. Chipps,Eric Benedetti,David O. Zamora,Dongseok Choi,Larry L. David,Justine R. Smith +10 more
TL;DR: Using gene expression and proteomic profiling, it has been possible to explore the molecular phenotype of the human retinal endothelial cell and contribute to understanding of the pathogenesis of these diseases.
Journal ArticleDOI
Risk of Ocular Complications in Patients with Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis
Andrew D. Dick,Andrew D. Dick,Namita Tundia,Rachael Sorg,Chen Zhao,Jingdong Chao,Avani Joshi,Martha Skup +7 more
TL;DR: Noninfectious intermediate uveitis, posterior uveitas, or panuveitis, particularly persistent disease, is associated with a substantial risk of ocular complications and Optimal treatment initiatives remain imperative to reduce the ocular complication-related burden.
References
More filters
Book
Statistical Analysis with Missing Data
TL;DR: This work states that maximum Likelihood for General Patterns of Missing Data: Introduction and Theory with Ignorable Nonresponse and large-Sample Inference Based on Maximum Likelihood Estimates is likely to be high.
Journal Article
EuroQol : a new facility for the measurement of health-related quality of life
Journal ArticleDOI
Statistical Analysis with Missing Data
Journal ArticleDOI
Longitudinal data analysis for discrete and continuous outcomes.
Scott L. Zeger,Kung-Yee Liang +1 more
TL;DR: A class of generalized estimating equations (GEEs) for the regression parameters is proposed, extensions of those used in quasi-likelihood methods which have solutions which are consistent and asymptotically Gaussian even when the time dependence is misspecified as the authors often expect.
Journal ArticleDOI
Validating the SF-36 health survey questionnaire: new outcome measure for primary care.
TL;DR: The SF-36 was able to detect low levels of ill health in patients who had scored 0 (good health) on the Nottingham health profile and is a promising new instrument for measuring health perception in a general population.