Real time electrocardiogram wave peak detection algorithm and its implementation on FPGA
20 Nov 2014-pp 204-209
TL;DR: A real time Electrocardiogram wave peak detection algorithm with low latency has been developed and can detect different component wave peaks, viz., P, Q, R, S and T from digitized samples.
Abstract: A real time Electrocardiogram wave peak detection algorithm with low latency has been developed. It can detect different component wave peaks, viz., P, Q, R, S and T from digitized samples. The algorithm has been implemented using Xilinx Spartan-III xc3s400tq144-5 FPGA module. For the purpose of detection of ECG wave peaks, during a training period of 6 second, a slope and polarity based signature is learned from the incoming ECG signal, which is sampled at 1 kHz frequency. These detected signatures of individual wave peaks of the concerned are then used for detection of subsequent individual component wave peaks. R, T and P waves are detected with 98.8%, 97.98% and 97.75% respectively using ptbdb and mitdb data from Physionet. The design consumed 35% resources of FPGA.
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01 Sep 2019
TL;DR: Experimental results indicate superiority of machine learning algorithms over the other three algorithms which are widely used in practice, and a linear support vector machine is found to be as good as other machine learning schemes.
Abstract: Circulating tumor cells in blood are identified by means of sequential peak detection taking into account the memory and real time applicability constraints. Three different spatial domain algorithms: derivative approach, energy detector and baseline method are compared with three different peak detection algorithms based on machine learning: linear and nonlinear support vector machines and artificial neural networks. Performance of the peak detection algorithms are tested on both synthetic and real data. Experimental results indicate superiority of machine learning algorithms over the other three algorithms which are widely used in practice. Due to Gaussianity assumption in the signal model, a linear support vector machine is found to be as good as other machine learning schemes.
Cites background from "Real time electrocardiogram wave pe..."
...Another computationally inexpensive approach that is implementable on an FPGA was proposed in [9], where the authors considered local maxima scalogram....
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...The real-time application is to be realized on a moderate FPGA chip, therefore, only the algorithms, which are computationally inexpensive and which fulfill storage requirements, i.e.: (a) Filtering and thresholding (b) Energy detector (c) Baseline method (d) Machine learning (ML) approaches are considered for comparison....
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...The complexity of training is irrelevant as it can be done off-line but the testing complexity is expected to be linear and the calculations are expected to be parallelizable such that full benefit of the FPGA can be obtained....
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...Since this approach is able to satisfy real time constraints such as speed and memory, it can be implemented on a field programmable gate array (FPGA) [8]....
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...Neural networks are highly parallelizable in software and hence for reasonably chosen numbers of layers and neurons, ANNs satisfy both the low complexity testing as well as the storage constraints to be implementable on an FPGA....
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References
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TL;DR: This work implemented and tested a final real-time QRS detection algorithm, using the optimized decision rule process, which has a sensitivity of 99.69 percent and positive predictivity of 98.77 percent when evaluated with the MIT/BIH arrhythmia database.
Abstract: We have investigated the quantitative effects of a number of common elements of QRS detection rules using the MIT/BIH arrhythmia database. A previously developed linear and nonlinear filtering scheme was used to provide input to the QRS detector decision section. We used the filtering to preprocess the database. This yielded a set of event vectors produced from QRS complexes and noise. After this preprocessing, we tested different decision rules on the event vectors. This step was carried out at processing speeds up to 100 times faster than real time. The role of the decision rule section is to discriminate the QRS events from the noise events. We started by optimizing a simple decision rule. Then we developed a progressively more complex decision process for QRS detection by adding new detection rules. We implemented and tested a final real-time QRS detection algorithm, using the optimized decision rule process. The resulting QRS detection algorithm has a sensitivity of 99.69 percent and positive predictivity of 99.77 percent when evaluated with the MIT/BIH arrhythmia database.
1,137 citations
"Real time electrocardiogram wave pe..." refers background or methods in this paper
...Real time QRS analysis by Tompkins and Hamilton [12] is implemented in FPGA hardware [13, 14]....
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...Hamilton and Tompkins [12], described a real time QRS complex detection algorithm where the signal is passed through a cascaded high-pass and low-pass integer filters....
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TL;DR: Compared with other artificial intelligence (AI) methods, the results demonstrate the efficiency of the proposed noninvasive method, and also show high accuracy for detecting ECG signals.
Abstract: This paper proposes a method for electrocardiogram (ECG) heartbeat discrimination using novel grey relational analysis (GRA). A typical ECG signal consists of the P-wave, QRS complexes and T-wave. We convert each QRS complexes to a Fourier spectrum from ECG signals, the spectrum varies with the rhythm origin and conduction path. The variations of power spectrum are observed in the range of 0-20 Hz in the frequency domain. To quantify the frequency components among the various ECG beats, GRA is performed to classify the cardiac arrhythmias. According to the AAMI (Association for the Advancement of Medical Instrumentation) recommended standard, heartbeat classes are recommended including the normal beat, supraventricular ectopic beat, bundle branch ectopic beat, ventricular ectopic beat, fusion beat and unknown beat. The method was tested on MIT-BIH (Massachusetts Institute of Technology-Beth Israel Hospital) arrhythmia database. Compared with other artificial intelligence (AI) methods, the results demonstrate the efficiency of the proposed noninvasive method, and also show high accuracy for detecting ECG signals.
158 citations
"Real time electrocardiogram wave pe..." refers background in this paper
...In [4], in a similar approach but instead of computing the cross correlation between the template and the signal as in eq....
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TL;DR: A QRS complex detector based on optimum predetection with a matched filter is described, which shows that differentiation reduces Gaussian error by √6 and errors caused by variable QRS amplitudes are close to zero.
Abstract: A QRS complex detector based on optimum predetection with a matched filter is described. In order to improve the accuracy of the QRS complex recognition under conditions of Gaussian noise and variable QRS amplitude, the first derivative of the e.c.g. was used with zero threshold detection. In addition, two nonlinear circuits cut off low amplitude noise and all spikes which appear for a fixed time after QRS detection. Calculation of errors shows that differentiation reduces Gaussian error by √6 and errors caused by variable QRS amplitudes are close to zero. This detector is especially useful with biotelemetry systems since it reduces many interferences due to patient movement and communication channel distortion.
136 citations
TL;DR: A new TU complex detection and characterization algorithm that consists of two stages, including the inclusion of U-wave characterization and a mathematical modeling stage, that avoids many of the problems of classic techniques when there is a low signal-to-noise ratio or when wave morphology is atypical.
Abstract: Presents a new TU complex detection and characterization algorithm that consists of two stages; the first is a mathematical modeling of the electrocardiographic segment after QRS complex; the second uses classic threshold comparison techniques, over the signal and its first and second derivatives, to determine the significant points of each wave. Later, both T and U waves are morphologically classified. Amongst the principal innovations of this algorithm is the inclusion of U-wave characterization and a mathematical modeling stage, that avoids many of the problems of classic techniques when there is a low signal-to-noise ratio or when wave morphology is atypical. The results of the algorithm validation with the recently appeared QT database are also shown. For T waves these results are better when compared to other existing algorithms. U-wave results cannot be contrasted with other algorithms as, to the authors' knowledge, none are available. Examples showing the causes of principal discrepancies between the authors' algorithm and the QT database annotations are also given, and some ways of attempting to improve and benefit from the proposed algorithm are suggested.
101 citations
"Real time electrocardiogram wave pe..." refers background in this paper
...[5] proposes an mathematical model based T wave recognition....
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11 Apr 1988
TL;DR: It is pointed out that in the analysis of transient signals such as those encounters in speech, or in certain kinds of image processing, standard Fourier analysis is often non satisfactory because the basic functions of the Fourier Analysis extend over infinite time, whereas the signals to be analyzed are short-time transients.
Abstract: It is pointed out that in the analysis of transient signals such as those encounters in speech, or in certain kinds of image processing, standard Fourier analysis is often non satisfactory because the basic functions of the Fourier analysis (sines, cosines, complex exponentials) extend over infinite time, whereas the signals to be analyzed are short-time transients. Reference is made to a method for dealing with transient signals which has recently appeared in the literature. The basis functions are referred to as wavelets, and they utilize time compression (or dilation) rather than a variation of frequency of the modulated sinusoid. Hence, all the wavelets have the same number of cycles. The analyzing wavelets must satisfy a few simple conditions, but are not otherwise specified. There is a wide latitude in the choice of these functions and they can be tailored to specific applications. The wavelets are founded on rigorous mathematical theory, and the expansions are robust. They are applied to detect ventricular delayed potentials (VLP) in the electrocardiogram. >
56 citations