Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway
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...…(Fragaria x ananassa), apple (Malus domestica), cauliflower (Brassica oleracea var botrytis), potato (Solanum tuberosum L.), bayberry (Myrica rubra), mangosteen (Garcinia mangostana L.), pear (Pyrus pyrifolia), and purple kale (Brassica oleracea var. acephala f. tricolor) (Hichri et al., 2011)....
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...The PA-related R2R3MYBs (sub-group 5) were first described for A. thaliana, with the R2R3MYB TT2 interacting with TT8 (bHLH) and TTG1 (WDR) to form the MBW complex [70,74]....
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...The R2R3MYBs regulating anthocyanin production in grape have been extensively studied over the last decade [74], butmore recently those for the PA [78e80] and flavonol [117] pathway branches have been identified, as well as the phenylpropanoid-related bHLHs and WDR [74,118]....
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...thaliana, with the R2R3MYB TT2 interacting with TT8 (bHLH) and TTG1 (WDR) to form the MBW complex [70,74]....
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..., there have also been significant advances in the depth of understanding of regulation of phenylpropanoid biosynthesis in important horticultural species, in particular grape and apple [74,116]....
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...The use of TFs as transgenes for modification of the biosynthesis of polyphenolics is now well proven, with many different genes shown to be effective and a large number of species successfully targeted [74,81]....
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789 citations
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Cites background from "Recent advances in the transcriptio..."
...1994; Hichri et al. 2011), biotic and abiotic stress (Segarra et al. 2009; Lippold et al. 2009), cell shape such as Am MIXTA (Noda et al. 1994), differentiation (Oppenheimer et al. 1991; Kang et al. 2009; Xie et al. 2010), hormone responses i.e. AtMYB2 (Urao et al. 1993), GAMYB and CpMYB (Gubler et…...
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References
57,055 citations
"Recent advances in the transcriptio..." refers background or methods in this paper
...Full-length protein sequences were aligned with Muscle (Edgar, 2004), and the phylogenetic tree was constructed according to the Neighbor–Joining method (Saitou and Nei, 1987)....
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...The bHLH domain is constituted of nearly 60 amino acids, and is characterized by the presence of 19 conserved amino acids, five in the basic region, five in the first helix, one in the loop, and finally eight amino acids in the second helix (Fig....
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40,349 citations
"Recent advances in the transcriptio..." refers methods in this paper
...3) (Toledo-Ortiz et al., 2003)....
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...The bootstrap consensus tree inferred from 2000 replicates is taken to represent the evolutionary history of the proteins (Felsenstein, 1985)....
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37,524 citations
Additional excerpts
...Edgar RC. 2004....
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29,021 citations
Additional excerpts
...MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0....
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...Phylogenetic analyses were conducted using MEGA4 (Tamura et al., 2007)....
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3,465 citations
"Recent advances in the transcriptio..." refers background or methods in this paper
...…accumulate in leaf epidermal cells, waxes, and trichomes, where they act as UV-B filters, but can also complex with DNA and protect it from oxidative damage (Sarma and Sharma, 1999; Harborne and Williams, 2000; Dixon, 2005; Dixon et al., 2005; Aron and Kennedy, 2008; Albert et al., 2009)....
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...All flavonoids display a C6–C3–C6 skeleton structure, except for the aurones (C6–C2–C6) (Harborne and Williams, 2000; Marais et al., 2006)....
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...Flavonoids also play a role in the interaction between plants and animals, as exemplified in leaves, where the concentration and nature of PAs determine the bitter taste and thus prevent feeding by herbivores (Harborne and Williams, 2000; Aron and Kennedy, 2008)....
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...Published by Oxford University Press [on behalf of the Society for Experimental Biology]....
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...Flavonoids also have demonstrated neuroprotective, anti-inflammatory, analgesic, bactericidal, fungicidal, and spasmolytic properties (Harborne and Williams, 2000; Sun et al., 2002)....
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