Recent progress in tissue optical clearing
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...Dehydration that occurs during clearing also contributes to the efficiency of the clearing process, beyond the fluid volume replacement by RI-adjusting reagents (Jiang and Wang, 2004; Rylander et al., 2006; Yu et al., 2011; Zhu et al., 2013)....
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...Although tissue clearing has a history that’s more than 100 years long (Spalteholz, 1914; Zhu et al., 2013), tissueclearing methods that can be implemented on practical timescales of days to weeks with a reasonable clearing efficiency for optic imaging are a much more recent development (Hama et…...
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...Although tissue clearing has a history that’s more than 100 years long (Spalteholz, 1914; Zhu et al., 2013), tissueclearing methods that can be implemented on practical timescales of days to weeks with a reasonable clearing efficiency for optic imaging are a much more recent development (Hama et al....
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"Recent progress in tissue optical c..." refers background in this paper
...Thus, better contrasting of these layers in OCT images was demonstrated for human rectum ex vivo [98] and human skin in vivo [99]....
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...The temporal dependences of OCT image contrast for the epidermis–dermis junction measured at low and high pressures for volunteers of different ages were associated with different dynamics of water inflow, in particular connected with the different balance of free and bonded water for the young and aged skin and different elasticity of the skin of the various age groups [99]....
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1,542 citations