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Recent progress of in situ formed gels for biomedical applications

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TLDR
In this review, in situ gelling systems were classified into chemical reaction driven gelation and physicochemical association driven gelations and the triggering mechanism involved in each process and the characteristics of each system are comparatively discussed.
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This article is published in Progress in Polymer Science.The article was published on 2013-03-01. It has received 350 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Injectable hydrogels for cartilage and bone tissue engineering.

TL;DR: The selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering are described and the biology of Cartilage and the bony ECM is summarized.
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Advancing biomaterials of human origin for tissue engineering

TL;DR: An exploration of the structural, mechanical, biochemical and biological information present in native human tissue for bioengineering applications is focused on to provide inspiration for the design of future biomaterials.
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Hydrogels in a historical perspective: from simple networks to smart materials.

TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
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Physical Double-Network Hydrogel Adhesives with Rapid Shape Adaptability, Fast Self-Healing, Antioxidant and NIR/pH Stimulus-Responsiveness for Multidrug-Resistant Bacterial Infection and Removable Wound Dressing

TL;DR: In vivo experiments prove that the hydrogels have good hemostasis of skin trauma and high killing ratio for methicillin‐resistant staphylococcus aureus and achieve better wound closure and healing of skin incision than medical glue and surgical suture.
References
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Journal ArticleDOI

Matrix elasticity directs stem cell lineage specification.

TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology†

TL;DR: This work highlights recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for biomedical and biological applications and shows how such systems' intelligent behavior can be used in sensors, microarrays, and imaging.
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Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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