Recent trends in the prevalence of Crohn's disease and ulcerative colitis in a commercially insured US population.
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...5% in North America.(11,12) Similar high prevalence values have been reported in Northern Europe (e....
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...Since 2000, the prevalence of IBD has ranged from 0.3% to 0.5% in North America.11,12 Similar high prevalence values have been reported in Northern Europe (e.g., United Kingdom and Scandinavia),13,14 Western Europe (e.g., Spain and Germany),15,16 and Oceania (e.g., New Zealand).17 What began as a handful of cases of ulcerative colitis, followed by Crohn’s disease, in the early 1900s in Western countries has grown to millions of individuals afflicted with IBD in North America, Europe, and Oceania.18,19 The steady increase in the prevalence of IBD coincided with the great acceleration of the human population in the last half of the 20th century.6 During this M AN US CR IP T AC CE PT ED time the incidence of Crohn’s disease and ulcerative colitis sharply increased; a finding consistently demonstrated by more than 200 epidemiologic studies investigating IBD in Western countries during the 20th century (Figure 1).10 Since the start of the 21st century, the incidence of IBD is changing in Western countries....
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"Recent trends in the prevalence of ..." refers result in this paper
...These results are similar to those reported in other US and Canadian studies [3, 4, 6, 13]....
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666 citations
"Recent trends in the prevalence of ..." refers methods in this paper
...The case definition used to identify prevalent cases of IBD was adapted from a previously validated University of Manitoba IBD Epidemiology Database definition [8] and has been used in prior epidemiological studies of IBD [3, 9–12]....
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622 citations
"Recent trends in the prevalence of ..." refers background in this paper
...The prevalence of CD has been reported to have increased between 1991 and 2001 [5] and that of both CD and UC to have increased between 2001 and 2005 [14]....
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...in Olmsted County, MN (115 and 107 per 100,000 for CD and UC, respectively) [5, 6]....
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597 citations
"Recent trends in the prevalence of ..." refers background or result in this paper
...to administrative case definitions that have been previously validated in the USA and Canada [1, 2, 13], the specific case definition has not been validated in this database....
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...Although similar Table 5 Standardized prevalence estimates of CD and UC colitis in a commercially insured US population (2004–2009) Age group 2004–2005 2006–2007 2008–2009 CD UC CD UC CD UC Pediatric (age \20 years) Prevalence per 100,000 (95 % CI)a 43.0 (42.6–43.5) 27.3 (27.0–27.7) 45.2 (44.7–45.6) 27.5 (27.2–27.9) 48.0 (47.5–48.5) 28.7 (28.3–29.0) Adult (age C20 years) Prevalence per 100,000 (95 % CI)a 213.6 (213.0–214.3) 234.9 (234.2–235.6) 230.3 (229.5–230.9) 246.5 (245.8–247.2) 235.6 (234.9–236.3) 248.1 (247.4–248.9) CI confidence interval, CD Crohn’s disease, UC ulcerative colitis a Exact 95 % confidence limits were calculated using a variation on the Wilson Score confidence interval method to administrative case definitions that have been previously validated in the USA and Canada [1, 2, 13], the specific case definition has not been validated in this database....
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...reported pediatric-specific prevalence estimates ranging from 31 to 71 per 100,000 for CD and 18–31 per 100,000 for UC [13]....
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...These results are similar to those reported in other US and Canadian studies [3, 4, 6, 13]....
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582 citations