Recovery of laryngeal function after intraoperative injury to the recurrent laryngeal nerve
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TLDR
This review aims to provide an update on the current understandings of surgically-induced injury to the laryngeal nerves to clarify any differences between the transient and permanent injury of the RLN.Abstract:
Loss of function in the recurrent laryngeal nerve (RLN) during thyroid/parathyroid surgery, despite a macroscopically intact nerve, is a challenge which highlights the sensitivity and complexity of laryngeal innervation. Furthermore, the uncertain prognosis stresses a lack of capability to diagnose the reason behind the impaired function. There is a great deal of literature considering risk factors, surgical technique and mechanisms outside the nerve affecting the incidence of RLN paresis during surgery. To be able to prognosticate recovery in cases of laryngeal dysfunction and voice changes after thyroid surgery, the surgeon would first need to define the presence, location, and type of laryngeal nerve injury. There is little data describing the events within the nerve and the neurobiological reasons for the impaired function related to potential recovery and prognosis. In addition, very little data has been presented in order to clarify any differences between the transient and permanent injury of the RLN. This review aims, from an anatomical and neurobiological perspective, to provide an update on the current understandings of surgically-induced injury to the laryngeal nerves.read more
Citations
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Application of transoral continuous intraoperative neuromonitoring in natural orifice transluminal endoscopic surgery for thyroid disease: a preliminary study.
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References
More filters
Journal ArticleDOI
Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF
Ronald W. Oppenheim,Lucien J. Houenou,James E. Johnson,Leu-Fen H. Lin,Linxi Li,Albert C. Lo,Ann L. Newsome,David Prevette,Siwei Wang +8 more
TL;DR: Glial-cell-line-derived neurotrophic factor (GDNF), a potent neurotrophicfactor that enhances survival of mammalian midbrain dopaminergic neurons16,17, rescues developing avian motor neurons from natural programmed cell death in vivo and promotes the survival of enriched populations of cultured motor neurons.
Journal ArticleDOI
Peripheral nerve regeneration.
Francis J. Liuzzi,Bruce Tedeschi +1 more
TL;DR: Although recent data suggest that neurotropic factors within the adult nerve can influence the sorting of regenerating axons, clinical and experimental data indicate that physical constraints of nerve cytoarchitecture can override those tropic factors.
Journal ArticleDOI
Regulation of growth cone behavior by calcium.
Stanley B. Kater,LR Mills +1 more
TL;DR: The role of intracellular calcium in the regulation of growth cone behaviors is considered and a working hypothesis stated, “if [intracellular] calcium falls below an optimal level, or rises significantly above it, growth cone motility and neurite outgrowth are inhibited” is put forward.
Journal ArticleDOI
Nogo and axon regeneration
TL;DR: In vivo applications of Nogo neutralizing antibodies, peptides blocking the Nogo receptor subunit NgR, or blockers of the postreceptor components Rho-A and ROCK induce long-distance axonal regeneration and compensatory sprouting, accompanied by an impressive enhancement of functional recovery, in the rat and mouse spinal cord.
Journal ArticleDOI
Calcium regulation of the neuronal growth cone.
TL;DR: Ca 2+ may act as a common integrator of environmental cues that influence neurite outgrowth and synaptogenesis, and in this way may play a key role in the establishment and modulation of brain circuitry.
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