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Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation.

TL;DR: A Recurrent Convolutional Neural Network (RCNN) based on U-Net as well as a Recurrent Residual convolutional neural Network (RRCNN), which are named RU-Net and R2U-Net respectively are proposed, which show superior performance on segmentation tasks compared to equivalent models including U-nets and residual U- net.
Abstract: Deep learning (DL) based semantic segmentation methods have been providing state-of-the-art performance in the last few years. More specifically, these techniques have been successfully applied to medical image classification, segmentation, and detection tasks. One deep learning technique, U-Net, has become one of the most popular for these applications. In this paper, we propose a Recurrent Convolutional Neural Network (RCNN) based on U-Net as well as a Recurrent Residual Convolutional Neural Network (RRCNN) based on U-Net models, which are named RU-Net and R2U-Net respectively. The proposed models utilize the power of U-Net, Residual Network, as well as RCNN. There are several advantages of these proposed architectures for segmentation tasks. First, a residual unit helps when training deep architecture. Second, feature accumulation with recurrent residual convolutional layers ensures better feature representation for segmentation tasks. Third, it allows us to design better U-Net architecture with same number of network parameters with better performance for medical image segmentation. The proposed models are tested on three benchmark datasets such as blood vessel segmentation in retina images, skin cancer segmentation, and lung lesion segmentation. The experimental results show superior performance on segmentation tasks compared to equivalent models including U-Net and residual U-Net (ResU-Net).
Citations
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Journal ArticleDOI
TL;DR: This survey presents a brief survey on the advances that have occurred in the area of Deep Learning (DL), starting with the Deep Neural Network and goes on to cover Convolutional Neural Network, Recurrent Neural Network (RNN), and Deep Reinforcement Learning (DRL).
Abstract: In recent years, deep learning has garnered tremendous success in a variety of application domains. This new field of machine learning has been growing rapidly and has been applied to most traditional application domains, as well as some new areas that present more opportunities. Different methods have been proposed based on different categories of learning, including supervised, semi-supervised, and un-supervised learning. Experimental results show state-of-the-art performance using deep learning when compared to traditional machine learning approaches in the fields of image processing, computer vision, speech recognition, machine translation, art, medical imaging, medical information processing, robotics and control, bioinformatics, natural language processing, cybersecurity, and many others. This survey presents a brief survey on the advances that have occurred in the area of Deep Learning (DL), starting with the Deep Neural Network (DNN). The survey goes on to cover Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), including Long Short-Term Memory (LSTM) and Gated Recurrent Units (GRU), Auto-Encoder (AE), Deep Belief Network (DBN), Generative Adversarial Network (GAN), and Deep Reinforcement Learning (DRL). Additionally, we have discussed recent developments, such as advanced variant DL techniques based on these DL approaches. This work considers most of the papers published after 2012 from when the history of deep learning began. Furthermore, DL approaches that have been explored and evaluated in different application domains are also included in this survey. We also included recently developed frameworks, SDKs, and benchmark datasets that are used for implementing and evaluating deep learning approaches. There are some surveys that have been published on DL using neural networks and a survey on Reinforcement Learning (RL). However, those papers have not discussed individual advanced techniques for training large-scale deep learning models and the recently developed method of generative models.

922 citations

Posted Content
TL;DR: This report presents a brief survey on development of DL approaches, including Deep Neural Network (DNN), Convolutional neural network (CNN), Recurrent Neural network (RNN) including Long Short Term Memory (LSTM) and Gated Recurrent Units (GRU), Auto-Encoder (AE), Deep Belief Network (DBN), Generative Adversarial Network (GAN), and Deep Reinforcement Learning (DRL).
Abstract: Deep learning has demonstrated tremendous success in variety of application domains in the past few years. This new field of machine learning has been growing rapidly and applied in most of the application domains with some new modalities of applications, which helps to open new opportunity. There are different methods have been proposed on different category of learning approaches, which includes supervised, semi-supervised and un-supervised learning. The experimental results show state-of-the-art performance of deep learning over traditional machine learning approaches in the field of Image Processing, Computer Vision, Speech Recognition, Machine Translation, Art, Medical imaging, Medical information processing, Robotics and control, Bio-informatics, Natural Language Processing (NLP), Cyber security, and many more. This report presents a brief survey on development of DL approaches, including Deep Neural Network (DNN), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN) including Long Short Term Memory (LSTM) and Gated Recurrent Units (GRU), Auto-Encoder (AE), Deep Belief Network (DBN), Generative Adversarial Network (GAN), and Deep Reinforcement Learning (DRL). In addition, we have included recent development of proposed advanced variant DL techniques based on the mentioned DL approaches. Furthermore, DL approaches have explored and evaluated in different application domains are also included in this survey. We have also comprised recently developed frameworks, SDKs, and benchmark datasets that are used for implementing and evaluating deep learning approaches. There are some surveys have published on Deep Learning in Neural Networks [1, 38] and a survey on RL [234]. However, those papers have not discussed the individual advanced techniques for training large scale deep learning models and the recently developed method of generative models [1].

550 citations


Cites background from "Recurrent Residual Convolutional Ne..."

  • ...Very recent, an improved version of U-Net[300] with Recurrent Residual Convolutional Neural Networks (RRCNN) which is named R2U-Net [301]....

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Journal ArticleDOI
TL;DR: This article provides a detailed review of the solutions above, summarizing both the technical novelties and empirical results, and compares the benefits and requirements of the surveyed methodologies and provides recommended solutions.

487 citations


Cites background from "Recurrent Residual Convolutional Ne..."

  • ...blocks Alom et al. (2018), dense convolution blocks Li et al....

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  • ...State-of-the-art architectures now benefit from re-designed skip connections Zhou et al. (2018b), residual convolution blocks Alom et al. (2018), dense convolution blocks Li et al. (2018), attention mechanisms Oktay et al. (2018), hybrid squeeze-excitation modules Roy et al. (2018), to name a few....

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Journal ArticleDOI
TL;DR: Wang et al. as discussed by the authors proposed Deformable U-Net (DUNet), which exploits the retinal vessels' local features with a U-shape architecture, in an end-to-end manner for retinal vessel segmentation.
Abstract: Automatic segmentation of retinal vessels in fundus images plays an important role in the diagnosis of some diseases such as diabetes and hypertension. In this paper, we propose Deformable U-Net (DUNet), which exploits the retinal vessels’ local features with a U-shape architecture, in an end to end manner for retinal vessel segmentation. Inspired by the recently introduced deformable convolutional networks, we integrate the deformable convolution into the proposed network. The DUNet, with upsampling operators to increase the output resolution, is designed to extract context information and enable precise localization by combining low-level features with high-level ones. Furthermore, DUNet captures the retinal vessels at various shapes and scales by adaptively adjusting the receptive fields according to vessels’ scales and shapes. Public datasets: DRIVE, STARE, CHASE_DB1 and HRF are used to test our models. Detailed comparisons between the proposed network and the deformable neural network, U-Net are provided in our study. Results show that more detailed vessels can be extracted by DUNet and it exhibits state-of-the-art performance for retinal vessel segmentation with a global accuracy of 0.9566/0.9641/0.9610/0.9651 and AUC of 0.9802/0.9832/0.9804/0.9831 on DRIVE, STARE, CHASE_DB1 and HRF respectively. Moreover, to show the generalization ability of the DUNet, we use another two retinal vessel data sets, i.e., WIDE and SYNTHE, to qualitatively and quantitatively analyze and compare with other methods. Extensive cross-training evaluations are used to further assess the extendibility of DUNet. The proposed method has the potential to be applied to the early diagnosis of diseases.

448 citations

Journal ArticleDOI
TL;DR: A narrative literature review examines the numerous developments and breakthroughs in the U-net architecture and provides observations on recent trends, and discusses the many innovations that have advanced in deep learning and how these tools facilitate U-nets.
Abstract: U-net is an image segmentation technique developed primarily for image segmentation tasks. These traits provide U-net with a high utility within the medical imaging community and have resulted in extensive adoption of U-net as the primary tool for segmentation tasks in medical imaging. The success of U-net is evident in its widespread use in nearly all major image modalities, from CT scans and MRI to X-rays and microscopy. Furthermore, while U-net is largely a segmentation tool, there have been instances of the use of U-net in other applications. Given that U-net’s potential is still increasing, this narrative literature review examines the numerous developments and breakthroughs in the U-net architecture and provides observations on recent trends. We also discuss the many innovations that have advanced in deep learning and discuss how these tools facilitate U-net. In addition, we review the different image modalities and application areas that have been enhanced by U-net.

425 citations


Cites methods from "Recurrent Residual Convolutional Ne..."

  • ...[52], [66] devised a U-net model containing both recurrent connections and residual connections....

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References
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55,235 citations


"Recurrent Residual Convolutional Ne..." refers background or methods in this paper

  • ...Convolutional Neural Network (DCNN) models have been proposed such as AlexNet [1], VGG [5], GoogleNet [6], Residual Net [7], DenseNet [8], and CapsuleNet [9][65]....

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  • ...SegNet consists of two parts, one is the encoding network which is a 13-layer VGG16 network [5], and the corresponding decoding network uses pixel-wise classification layers....

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  • ...Contrarily, the work presented in [61] evaluated VGG-16 and Incpetion-V3 models for skin lesion segmentation, but those networks contained around 138M and 23M network parameters respectively. network, and fourth column show the final resulting after performing thresholding with 0.5....

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  • ...In the last few years, a lot of models have been proposed that have proved that deeper networks are better for recognition and segmentation tasks [5]....

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  • ...However, training very deep models is difficult due to the vanishing gradient problem, which is resolved by implementing modern activation functions such as Rectified Linear Units (ReLU) or Exponential Linear Units (ELU) [5,6]....

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01 Jan 2015
TL;DR: In this paper, the authors investigated the effect of the convolutional network depth on its accuracy in the large-scale image recognition setting and showed that a significant improvement on the prior-art configurations can be achieved by pushing the depth to 16-19 layers.
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40,257 citations