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Journal ArticleDOI

Reimagining Innovation Amid the COVID-19 Pandemic: Insights From the WISH Innovation Programme.

01 Jan 2021-Frontiers in Public Health (Frontiers Media SA)-Vol. 9, pp 678768-678768
TL;DR: The World Innovation Summit for Health (WISH) hosts two innovation competitions as part of its biennial healthcare conference as discussed by the authors, and during the COVID-19 pandemic, WISH received more than 350 applications for both competitions, of which 31 were shortlisted to showcase at the WISH 2020 virtual summit.
Abstract: The World Innovation Summit for Health (WISH) hosts two innovation competitions as part of its biennial healthcare conference. During the COVID-19 pandemic, WISH received more than 350 applications for both competitions, of which 31 were shortlisted to showcase at the WISH 2020 virtual summit. Of the 31 showcasing innovations, 11 (35.5%) had suggested an alternative use to their innovation as a contribution to the global fight against COVID-19. As such, this article explores the apparent and urgent need for the repurposing of healthcare innovations to reduce the costs and time associated with the conventional approach, in order to best respond to the demands of the global pandemic.

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Journal ArticleDOI
TL;DR: Approaches used for drug repurposing (also known as drug repositioning) are presented, the challenges faced by the repurpose community are discussed, and innovative ways by which these challenges could be addressed are recommended to help realize the full potential of drugRepurposing.
Abstract: Given the high attrition rates, substantial costs and slow pace of new drug discovery and development, repurposing of 'old' drugs to treat both common and rare diseases is increasingly becoming an attractive proposition because it involves the use of de-risked compounds, with potentially lower overall development costs and shorter development timelines. Various data-driven and experimental approaches have been suggested for the identification of repurposable drug candidates; however, there are also major technological and regulatory challenges that need to be addressed. In this Review, we present approaches used for drug repurposing (also known as drug repositioning), discuss the challenges faced by the repurposing community and recommend innovative ways by which these challenges could be addressed to help realize the full potential of drug repurposing.

2,365 citations

Journal ArticleDOI
TL;DR: Telemedicine for Covid-19’s payment and regulatory structures, licensing, credentialing, and implementation take time to work through, but health systems that have a...
Abstract: Virtually Perfect? Telemedicine for Covid-19 Telemedicine’s payment and regulatory structures, licensing, credentialing, and implementation take time to work through, but health systems that have a...

2,130 citations

Journal ArticleDOI
TL;DR: This article highlights key requirements for telehealth uptake, including flexible funding arrangements, training and accrediting the health workforce, to become a routinely used part of the health system.
Abstract: The current coronavirus (COVID-19) pandemic is again reminding us of the importance of using telehealth to deliver care, especially as means of reducing the risk of cross-contamination caused by close contact. For telehealth to be effective as part of an emergency response it first needs to become a routinely used part of our health system. Hence, it is time to step back and ask why telehealth is not mainstreamed. In this article, we highlight key requirements for this to occur. Strategies to ensure that telehealth is used regularly in acute, post-acute and emergency situations, alongside conventional service delivery methods, include flexible funding arrangements, training and accrediting our health workforce. Telehealth uptake also requires a significant change in management effort and the redesign of existing models of care. Implementing telehealth proactively rather than reactively is more likely to generate greater benefits in the long-term, and help with the everyday (and emergency) challenges in healthcare.

1,146 citations

Journal ArticleDOI
TL;DR: The role that telehealth has played in transforming healthcare delivery during the 3 phases of the U.S. COVID-19 pandemic is described and how people, process, and technology work together to support a successful telehealth transformation is examined.

986 citations

Journal ArticleDOI
TL;DR: The role of AI as a decisive technology to analyze, prepare us for prevention and fight with COVID-19 (Coronavirus) and other pandemics is reviewed and seven significant applications of AI for CO VID-19 pandemic are identified.
Abstract: Background and aims Healthcare delivery requires the support of new technologies like Artificial Intelligence (AI), Internet of Things (IoT), Big Data and Machine Learning to fight and look ahead against the new diseases. We aim to review the role of AI as a decisive technology to analyze, prepare us for prevention and fight with COVID-19 (Coronavirus) and other pandemics. Methods The rapid review of the literature is done on the database of Pubmed, Scopus and Google Scholar using the keyword of COVID-19 or Coronavirus and Artificial Intelligence or AI. Collected the latest information regarding AI for COVID-19, then analyzed the same to identify its possible application for this disease. Results We have identified seven significant applications of AI for COVID-19 pandemic. This technology plays an important role to detect the cluster of cases and to predict where this virus will affect in future by collecting and analyzing all previous data. Conclusions Healthcare organizations are in an urgent need for decision-making technologies to handle this virus and help them in getting proper suggestions in real-time to avoid its spread. AI works in a proficient way to mimic like human intelligence. It may also play a vital role in understanding and suggesting the development of a vaccine for COVID-19. This result-driven technology is used for proper screening, analyzing, prediction and tracking of current patients and likely future patients. The significant applications are applied to tracks data of confirmed, recovered and death cases.

858 citations