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Journal ArticleDOI

Response of adult rats to low dietary levels of essential amino acids.

A. K. Said, +1 more
- 01 Nov 1970 - 
- Vol. 100, Iss: 11, pp 1363-1375
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This article is published in Journal of Nutrition.The article was published on 1970-11-01. It has received 117 citations till now. The article focuses on the topics: Complete protein & Amino acid.

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Citations
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The optimum dietary amino acid pattern for growing pigs. 1. Experiments by amino acid deletion.

TL;DR: In this article, a series of nitrogen-balance experiments was carried out with growing pigs to determine the optimum balance amongst the amino acids in the diet, and the reduction in N retention when 20 % of a single amino acid was removed from the diet was used to calculate a dietary amino acid pattern in which each amino acid would he equally limiting.
Journal ArticleDOI

Amino acids and mTORC1: from lysosomes to disease

TL;DR: The involvement of a catabolic organelle in growth signaling may have important implications for the understanding of mTORC1-related pathologies.

Amino acids and mTORC1: from lysosomes to disease

TL;DR: In this paper, the authors placed the lysosome, a key mediator of cellular catabolism, at the core of mTORC1 regulation by amino acids.
Journal ArticleDOI

The optimum dietary amino acid pattern for growing pigs. 2. Requirements for maintenance and for tissue protein accretion.

TL;DR: It was estimated that both for maintenance and for protein accretion tyrosine could provide close to half the total phenylalanine+tyrosine needs and Cystine could supply close to two-thirds of the total sulphur amino acid needs.
Journal ArticleDOI

Preservation of Liver Protein Synthesis during Dietary Leucine Deprivation Occurs at the Expense of Skeletal Muscle Mass in Mice Deleted for eIF2 Kinase GCN2

TL;DR: It is indicated that loss of GCN2 eIF2 kinase activity shifts the normal maintenance of protein mass away from skeletal muscle to provide substrate for continued hepatic translation.
References
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The nutritive value of the wheat kernel and its milling products

TL;DR: In this article, the present shortage in the food supply of the world makes important every detail of knowledge concerning human nutrition, and even facts which seem academic need scrutiny, in case at some point or other they may find application in the direction of guidance for economy.
Journal ArticleDOI

Quantitative nutritional studies with water-soluble, chemically defined diets. VIII. The forced feeding of diets each lacking in one essential amino acid.

TL;DR: Rats bearing the rapidly growing Walker tumor were subjected to the deficient diets, and all gained in weight by an amount nearly equivalent to the weight of the tumor, the carcasses losing weight to about the same extent as their normal controls on the same diets.
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