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Journal ArticleDOI

Response of pineal lipid to hormone imbalances.

Gerald F. Hungerford, +1 more
- 01 Dec 1962 - 
- Vol. 71, Iss: 6, pp 936-942
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TLDR
It was concluded that the pineal gland may be implicated in sodium homeostasis, the mechanism remains unknown and all the procedures which defatted the Pineal gland had some effect on sodium metabolism.
Abstract
The effect of hormone imbalances on the amount of fat stainable with oil red 0 in the pineal gland of the rat was studied. It was found that treatment with angiotensin II or propylthiouracil depleted pineal lipid. Removal of the pituitary or combined castration and adrenalectomy also severely depleted pineal fat. On the other hand, the administration of desoxycorticosterone acetate tended to augment the amount of pineal lipid. Other treatments which were found to be without effect in altering the amount of pineal lipid included: thyroxine, testosterone, hydrocortisone, adrenaline, serotonin, ACTH, B-MSH, alloxan and castration. All the procedures which defatted the pineal gland had some effect on sodium metabolism. While it was concluded that the pineal gland may be implicated in sodium homeostasis, the mechanism remains unknown.

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Book ChapterDOI

Histological structure and cytology of the pineal organ in birds and mammals.

TL;DR: The findings that are functionally suggestive and those that are important in the design and interpretation of experiments purporting to demonstrate pineal function or activity are discussed in the chapter.
Book ChapterDOI

Control of Aldosterone Secretion

TL;DR: Additional stimulating and inhibiting factors from the posterior diencephalon and pineal gland may exist, but it now appears that, if they do, their physiological roles are minor.
Journal ArticleDOI

The epiphysis cerebri of the Weddell seal: its remarkable size and glandular pattern

TL;DR: A morphologic study of the pineal of the Weddell seal (Leptonichotes weddelli) was carried out during a whole polar year and Pinealocytes that are present only in the cortical region showed a clear seasonal variation in their lipidic content.
Book ChapterDOI

Endocrine and neurochemical aspects of pineal function.

TL;DR: The chapter indicates that the influence of pineal hormone-like substances on the reproductive system, elicited by environmental lighting conditions, seems to be the most important of the endocrine effects exerted by the pineal gland.
Journal ArticleDOI

Pineal gland in rats suffering from malignancy.

TL;DR: The results indicate that there is increased metabolic activity in the pineal glands of tumour bearing animals.
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