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Journal ArticleDOI

REVIEW ■ : Reorganization of Sensory Systems of Primates after Injury:

Jon H. Kaas, +2 more
- 01 Mar 1997 - 
- Vol. 3, Iss: 2, pp 123-130
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TLDR
The orderly representations of sensory surfaces in the brains of adult mammals have the capacity to reor ganize after injuries that deprive these representations of some of their normal sources of activation.
Abstract
The orderly representations of sensory surfaces in the brains of adult mammals have the capacity to reor ganize after injuries that deprive these representations of some of their normal sources of activation. Such reorganizations can be produced by injury that occurs peripherally, such as nerve damage or amputation, or after injury to the CNS, such as spinal cord damage or cortical lesion. These changes likely are mediated by a number of different mechanisms, and can be extensive and involve the growth of new connections. Finally, some types of reorganizations may help mediate the recovery of lost functions, whereas others may lead to sensory abnormalities and perceptual errors. NEUROSCIENTIST 3:123-130, 1997

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Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury

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Peripherally induced oromandibular dystonia

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References
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Journal ArticleDOI

Injury-Induced Reorganization of Somatosensory Cortex Is Accompanied by Reductions in GABA Staining

TL;DR: The regulation of the expression of GABA appears to be one mechanism for maintaining and altering cortical representations in monkeys surviving nerve injury for 2-5 months.
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Lesion-induced plasticity in the second somatosensory cortex of adult macaques

TL;DR: It is reported that, although removal of the entire postcentral hand representation does indeed leave the SII hand representation unresponsive to somatic stimulation initially, 6-8 weeks later this cortex is no longer silent and this massive somatotopic reorganization exceeds that previously observed in the postcentral cortex after peripheral nerve damage.
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NMDA receptors and plasticity in adult primate somatosensory cortex

TL;DR: Much of the cortical “recovery” that typically follows peripheral nerve injury in adult monkeys is apparently dependent on NMDA receptors and may well be due to Hebbian‐like changes in synaptic strength.
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Plasticity in the barrel cortex of the adult mouse: transient increase of GAD-immunoreactivity following sensory stimulation

TL;DR: It is reported that increased sensory stimulation, during four days, of a number of whisker follicles on the face of theAdult mouse results in an increased immunoreactivity of glutamic acid decarboxylase in the somatosensory cortex of the adult mouse.
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