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Open AccessJournal ArticleDOI

Revisiting HEp-2 Cell Image Classification

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TLDR
A framework to automate the identification of antigen patterns in the cell images is presented and suggests that the algorithm is comparable with the state-of-the-art approaches.
Abstract
The immune system in homo sapiens protects the body against diseases by identifying and attacking foreign pathogens. However, when the system misidentifies native cells as threats, it results in an auto-immune response. The auto-antibodies generated during this phenomenon may be identified through the indirect immunofluorescence test. An important constituent process of this test is the automated identification of antigen patterns in the cell images, which is the focus of this research. We perform a detailed literature review and present a framework to automate the identification of antigen patterns. The efficacy of the framework, demonstrated on the MIVIA ICPR 2012 HEp-2 Cell Contest and SNP HEp-2 Cell datasets, suggests that the algorithm is comparable with the state-of-the-art approaches.

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Citations
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Feature analysis for automatic classification of HEp-2 florescence patterns: Computer-aided diagnosis of auto-immune diseases

TL;DR: This work proposes feature extraction methods for automatic recognition of staining patterns of HEp-2 images to develop a Computer-Aided Diagnosis system and support the specialists' decision.
Journal ArticleDOI

A Deep Feature Extraction Method for HEp-2 Cell Image Classification

TL;DR: The results show that the proposed features manage to capture the distinctive characteristics of the different cell types while performing at least as well as the actual deep learning-based state-of-the-art methods in terms of discrimination.
Journal ArticleDOI

A deep learning AlexNet model for classification of red blood cells in sickle cell anemia

TL;DR: The proposed framework can classify 15 types of RBC shapes including normal in an automated manner with a deep AlexNet transfer learning model and shows that the cell's name classification prediction accuracy, sensitivity, specificity, and precision were achieved.
Journal ArticleDOI

A Strictly Unsupervised Deep Learning Method for HEp-2 Cell Image Classification.

TL;DR: A deep learning scheme is proposed that performs both the feature extraction and the cells’ discrimination through an end-to-end unsupervised paradigm that uses a deep convolutional autoencoder (DCAE) that performs feature extraction via an encoding–decoding scheme.
Journal ArticleDOI

A Dynamic Learning Method for the Classification of the HEp-2 Cell Images

TL;DR: A dynamic learning process is conducted with different networks taking different input variations in parallel in order to efficiently homogenize the features extracted from the images that have different intensity levels.
References
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TL;DR: This paper presents a method for extracting distinctive invariant features from images that can be used to perform reliable matching between different views of an object or scene and can robustly identify objects among clutter and occlusion while achieving near real-time performance.
Proceedings ArticleDOI

Beyond Bags of Features: Spatial Pyramid Matching for Recognizing Natural Scene Categories

TL;DR: This paper presents a method for recognizing scene categories based on approximate global geometric correspondence that exceeds the state of the art on the Caltech-101 database and achieves high accuracy on a large database of fifteen natural scene categories.
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Probability Estimates for Multi-class Classification by Pairwise Coupling

TL;DR: In this paper, the authors present two approaches for obtaining class probabilities, which can be reduced to linear systems and are easy to implement, and show conceptually and experimentally that the proposed approaches are more stable than the two existing popular methods: voting and the method by Hastie and Tibshirani (1998).
Book ChapterDOI

Region covariance: a fast descriptor for detection and classification

TL;DR: A fast method for computation of covariances based on integral images, and the performance of the covariance features is superior to other methods, as it is shown, and large rotations and illumination changes are also absorbed by the covariances matrix.
Journal Article

Region Covariance : A Fast Descriptor for Detection and Classification

TL;DR: In this paper, a fast method for computation of covariance matrices based on integral images is described, which is more general than the image sums or histograms, which were already published before, and with a series of integral images the covariances are obtained by a few arithmetic operations.
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