Risk Factors of Fatal Outcome in Hospitalized Subjects With Coronavirus Disease 2019 From a Nationwide Analysis in China.
Ruchong Chen,Wenhua Liang,Mei Jiang,Wei-jie Guan,Chen Zhan,Tao Wang,Chun-Li Tang,Ling Sang,Jiaxing Liu,Zhengyi Ni,Yu Hu,Lei Liu,Hong Shan,Chunliang Lei,Yi-xiang Peng,Li Wei,Yong Liu,Ya-hua Hu,Peng Peng,Jian-ming Wang,Ji-yang Liu,Zhong Chen,Gang Li,Zhi-jian Zheng,Shao-qin Qiu,Jie Luo,Chang-jiang Ye,Shao-yong Zhu,Xiaoqing Liu,Linling Cheng,Feng Ye,Jinping Zheng,Nuofu Zhang,Yimin Li,Jianxing He,Shiyue Li,Nanshan Zhong +36 more
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TLDR
The proposed nomogram accurately predict clinical outcomes of patients with COVID-19 based on individual characteristics and has sufficient discriminatory power with the C-index of 0.91.About:
This article is published in Chest.The article was published on 2020-07-01 and is currently open access. It has received 490 citations till now. The article focuses on the topics: Nomogram & Hazard ratio.read more
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Genomewide Association Study of Severe Covid-19 with Respiratory Failure.
David Ellinghaus,Frauke Degenhardt,Luis Bujanda,Maria Buti,Agustín Albillos,Pietro Invernizzi,J. Fernández,Daniele Prati,Guido Baselli,Rosanna Asselta,Marit Mæhle Grimsrud,Chiara Milani,Fatima Aziz,Jan Christian Kässens,Sandra May,Mareike Wendorff,Lars Wienbrandt,Florian Uellendahl-Werth,Tenghao Zheng,Xiaoli Yi,Raúl de Pablo,Adolfo Garrido Chercoles,Adriana Palom,Alba Estela Garcia-Fernandez,Francisco Rodriguez-Frias,Alberto Zanella,Alessandra Bandera,Alessandro Protti,Alessio Aghemo,Ana Lleo,Andrea Biondi,Andrea Caballero-Garralda,Andrea Gori,Anja Tanck,Anna Carreras Nolla,Anna Latiano,Anna Ludovica Fracanzani,Anna Peschuck,Antonio Julià,Antonio Pesenti,Antonio Voza,David Jiménez,Beatriz Mateos,Beatriz Nafria Jimenez,Carmen Quereda,Cinzia Paccapelo,Christoph Gassner,Claudio Angelini,Cristina Cea,Aurora Solier,David Pestana,Eduardo Muñiz-Diaz,Elena Sandoval,Elvezia Maria Paraboschi,Enrique Navas,Félix García Sánchez,Ferruccio Ceriotti,F. Martinelli-Boneschi,Flora Peyvandi,Francesco Blasi,Luis Téllez,Albert Blanco-Grau,Georg Hemmrich-Stanisak,Giacomo Grasselli,Giorgio Costantino,Giulia Cardamone,Giuseppe Foti,Serena Aneli,Hayato Kurihara,Hesham ElAbd,Ilaria My,Iván Galván-Femenía,Javier Martin,Jeanette Erdmann,José Ferrusquía-Acosta,Koldo Garcia-Etxebarria,Laura Izquierdo-Sanchez,Laura Rachele Bettini,Lauro Sumoy,Leonardo Terranova,Leticia Moreira,Luigi Santoro,Luigia Scudeller,Francisco Mesonero,Luisa Roade,Malte C. Rühlemann,Marco Schaefer,Maria Carrabba,Mar Riveiro-Barciela,Maria Eloina Figuera Basso,Maria Grazia Valsecchi,María Hernández-Tejero,Marialbert Acosta-Herrera,Mariella D'Angiò,Marina Baldini,Marina Cazzaniga,Martin Schulzky,Maurizio Cecconi,Michael Wittig,Michele Ciccarelli,Miguel Rodríguez-Gandía,Monica Bocciolone,Monica Miozzo,Nicola Montano,Nicole Braun,Nicoletta Sacchi,Nilda Martinez,Onur Özer,Orazio Palmieri,Paola Faverio,Paoletta Preatoni,Paolo Bonfanti,Paolo Omodei,Paolo Tentorio,Pedro Castro,Pedro M. Rodrigues,Aaron Blandino Ortiz,Rafael de Cid,Ricard Ferrer,Roberta Gualtierotti,Rosa Nieto,Siegfried Goerg,Salvatore Badalamenti,Sara Marsal,Giuseppe Matullo,Serena Pelusi,Simonas Juzenas,Stefano Aliberti,Valter Monzani,Victor Moreno,Tanja Wesse,Tobias L. Lenz,Tomás Pumarola,Valeria Rimoldi,Silvano Bosari,Wolfgang Albrecht,Wolfgang Peter,Manuel Romero-Gómez,Mauro D'Amato,Stefano Duga,Jesus M. Banales,Johannes R. Hov,Trine Folseraas,Luca Valenti,Andre Franke,Tom H. Karlsen +145 more
TL;DR: A 3p21.31 gene cluster is identified as a genetic susceptibility locus in patients with Covid-19 with respiratory failure and a potential involvement of the ABO blood-group system is confirmed.
Journal ArticleDOI
Acute kidney injury in patients hospitalized with COVID-19.
Jamie S. Hirsch,Jia H. Ng,Daniel W. Ross,Purva Sharma,Hitesh H. Shah,Richard Barnett,Azzour D. Hazzan,Steven Fishbane,Kenar D. Jhaveri +8 more
TL;DR: AKI occurs frequently among patients with Covid-19 disease, it occurs early and in temporal association with respiratory failure and is associated with a poor prognosis.
Journal ArticleDOI
Chest CT score in COVID-19 patients: correlation with disease severity and short-term prognosis.
Marco Francone,Franco Iafrate,Giorgio Maria Masci,Simona Coco,Francesco Cilia,Lucia Manganaro,Valeria Panebianco,Chiara Andreoli,Maria Chiara Colaiacomo,Maria Antonella Zingaropoli,Maria Rosa Ciardi,Claudio Maria Mastroianni,Francesco Pugliese,Francesco Alessandri,Ombretta Turriziani,Paolo Ricci,Carlo Catalano +16 more
TL;DR: The preliminary data suggest the potential role of CT score for predicting the outcome of SARS-CoV-2 patients' outcome and multivariate analysis demonstrated that CT parenchymal assessment may more accurately reflect short-term outcome.
Journal ArticleDOI
Prognostic Factors for Severity and Mortality in Patients Infected with COVID-19: A Systematic Review
Ariel Izcovich,Martín Ragusa,Fernando Tortosa,María Andrea Lavena Marzio,Camila Agnoletti,Agustín Bengolea,Agustina Ceirano,Federico Espinosa,Ezequiel Alvarez Saavedra,Verónica Sanguine,Alfredo Tassara,Candelaria Cid,Hugo N Catalano,Arnav Agarwal,Farid Foroutan,Gabriel Rada +15 more
TL;DR: In this article, a systematic review is conducted to identify prognostic factors that may be used in decision-making related to the care of patients infected with SARS-CoV-2.
Journal ArticleDOI
Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis.
Bradley J Langford,Miranda So,Miranda So,Miranda So,Sumit Raybardhan,Valerie Leung,Jean-Paul R. Soucy,Duncan Westwood,Nick Daneman,Derek R. MacFadden +9 more
TL;DR: In this paper, the prevalence and associated factors of antibiotic prescribing in patients with SARS-CoV-2 infection were estimated in a randomized controlled trial with 30,623 patients.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
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