RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts
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Cites methods from "RNA in unexpected places: long non-..."
...Using our CRISPRi library design algorithm, we selected and cloned up to three sgRNAs each targeting six characterized lncRNAs (GAS5,H19,MALAT1,NEAT1, TERC, XIST) (Geisler and Coller, 2013) with good evidence of expression in K562 cells....
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Cites background from "RNA in unexpected places: long non-..."
...Taking into consideration what has been published to date, different main groups of action for lncRNAs in accordance to Geisler and Coller (80) can be catalogued, where lncRNAs are grouped according to the level of acting on expression changes: lncRNAs acting as regulators of transcription; this takes place in the nucleus as well as in the cytoplasm by interacting of lncRNAs with transcription factors for instance....
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References
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