RNA-Seq: a revolutionary tool for transcriptomics
Citations
112 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...Deep sequencing may increase the dynamic range of detectable genes expressed to include low or highly expressed genes that may not be detectable or differentiated by microarray (Wang et al. 2009), and this may decrease or eliminate drop-outs....
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...Deep sequencing may increase the dynamic range of detectable genes expressed to include low or highly expressed genes that may not be detectable or differentiated by microarray (Wang et al. 2009), and this may decrease or eliminate drop-outs....
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111 citations
111 citations
Cites methods from "RNA-Seq: a revolutionary tool for t..."
...been widely employed in several studies as a powerful tool for transcriptomics (4)....
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111 citations
Cites methods from "RNA-Seq: a revolutionary tool for t..."
...In the next decade, next-generation sequencing technologies such as RNA-seq (Wang et al, 2009) promises to accelerate the pace and depth of discovery, further strengthening GEP as a method for cancer classification by directly determining transcript identity, structure, and abundance at the single-base level....
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...In the next decade, next-generation sequencing technologies such as RNA-seq (Wang et al, 2009) promises to accelerate the pace and depth of discovery, further strengthening GEP as a method for cancer classification by directly determining transcript identity, structure, and abundance at the…...
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111 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...Moreover, sequence reads from a specific individual can contain sufficient information to potentially identify and genetically characterize that person, raising privacy concerns....
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References
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"RNA-Seq: a revolutionary tool for t..." refers methods in this paper
...There are several programs for mapping reads to the genome, including ELAND, SOA...
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