RNA-Seq: a revolutionary tool for transcriptomics
Citations
91 citations
91 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...Transcriptome analysis is essential in interpreting the functional elements of the genome and reveals the molecular constituents of cells and tissues [27,28]....
[...]
91 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...For example, massively parallel sequencing of cellular mRNA population...
[...]
91 citations
Cites methods from "RNA-Seq: a revolutionary tool for t..."
...Orthology was confirmed through construction of maximum-likelihood trees using Jalview (Waterhouse et al. 2009) and PhyML (Guindon et al. 2010) (Fig....
[...]
91 citations
Cites background or methods from "RNA-Seq: a revolutionary tool for t..."
...2012), arrays in general are less sensitive than RNA-seq and have limited ability to detect alternative spliced mRNA isoforms (Wang et al. 2009; McGettigan, 2013)....
[...]
...We employed this strategy because although RNA-seq data offer unprecedented resolution and reproducibility (Marioni et al. 2008; Wang et al. 2009), analysis of complete transcripts rather than individual probes on subregions of transcripts is challenging (Wagner et al....
[...]
...We employed this strategy because although RNA-seq data offer unprecedented resolution and reproducibility (Marioni et al. 2008; Wang et al. 2009), analysis of complete transcripts rather than individual probes on subregions of transcripts is challenging (Wagner et al. 2012)....
[...]
...Although not completely replacing other technologies, such as microarray (Kogenaru et al. 2012), arrays in general are less sensitive than RNA-seq and have limited ability to detect alternative spliced mRNA isoforms (Wang et al. 2009; McGettigan, 2013)....
[...]
References
12,293 citations
4,437 citations
2,927 citations
2,834 citations
2,729 citations
"RNA-Seq: a revolutionary tool for t..." refers methods in this paper
...There are several programs for mapping reads to the genome, including ELAND, SOA...
[...]