RNA-Seq: a revolutionary tool for transcriptomics
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87 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...It has several advantages over microarray studies: RNA-seq has low background noise, can identify a larger dynamic ranges of expression level, can distinguish among different isoforms and allelic expression, and is able to provide single base resolution and measurement of each transcript (73)....
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...Transcriptomics is the study of the complete set of mRNA transcripts in a cell and the quantity of each transcript (73)....
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86 citations
86 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...RNA sequencing (RNA-seq) has transformed our under-standing of gene expression and transcriptional regulation (Lister et al. 2008; Mortazavi et al. 2008; Nagalakshmi et al. 2008; Wang et al. 2009)....
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86 citations
86 citations
References
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"RNA-Seq: a revolutionary tool for t..." refers methods in this paper
...There are several programs for mapping reads to the genome, including ELAND, SOA...
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