RNA-Seq: a revolutionary tool for transcriptomics
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182 citations
182 citations
Cites background or methods from "RNA-Seq: a revolutionary tool for t..."
...Recent studies, for example, have reported a role for small regulatory RNAs in M. tuberculosis [58], and there is little doubt more regulatory RNAs will soon be identified by RNA-seq [57]....
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...used to study both the host and the pathogen is sequence-based transcriptomics, in which gene expression is measured by whole genome sequencing of RNA transcripts; a method referred to as RNA-seq [57]....
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...Another approach increasingly being PLoS Pathogens | www.plospathogens.org 5 October 2009 | Volume 5 | Issue 10 | e1000600 used to study both the host and the pathogen is sequence-based transcriptomics, in which gene expression is measured by whole genome sequencing of RNA transcripts; a method referred to as RNA-seq [57]....
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...tuberculosis [58], and there is little doubt more regulatory RNAs will soon be identified by RNA-seq [57]....
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...RNA-seq is particularly useful for genome-wide studies of small regulatory RNAs, as such studies are more difficult to perform using standard DNA microarrays....
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181 citations
Cites result from "RNA-Seq: a revolutionary tool for t..."
...For a more detailed comparison of current HTS technologies and how these compare with microarray-based methods, we refer the reader to a recent review by Wang et al. (2009)....
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181 citations
Cites background from "RNA-Seq: a revolutionary tool for t..."
...Recently developed RNA deep sequencing technologies, such as Solexa/Illumina RNA-seq and Digital gene expression (DGE), have dramatically changed the way immune-related genes in fish are identified because these technologies facilitate the investigation of the functional complexity of transcriptomes [11,12]....
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181 citations
References
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"RNA-Seq: a revolutionary tool for t..." refers methods in this paper
...There are several programs for mapping reads to the genome, including ELAND, SOA...
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